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O Ural

Publications and source records attributed to O Ural.

8 recordsLinked to original sources
PubMed2004

Urethral cultures in patients with spinal cord injury.

STUDY DESIGN: Prospective analysis. OBJECTIVES: To investigate the colonization of the distal urethra and bladder during the initial stages of rehabilitation in acute spinal-cord injury (SCI) and to examine the association between bacteriuria and colonization of the distal urethra. SETTING: Selcuk University Meram Faculty of Medicine, Konya, Turkey. METHODS: A total of 27 patients with SCI (13 females and 14 males) and 40 controls without evidence of disease of the urinary tract were studied. Cultures were taken from the patients who applied clean intermittent catheterization and compared with normal subjects. RESULTS: Escherichia coli was predominantly isolated from the urine and urethral cultures of both female and male SCI patients. Colonization of other bacteria in the urine and urethral cultures was similar in both female and male patients, except for Pseudomonas, which was colonized in male patients. In all, 72% of patients who had E. coli positive urethral cultures also had E. coli colonization in their simultaneous urine cultures. There was concordance between urethra and urine cultures concerning the growth of E. coli (P=0.82). When urethral cultures collected 1 week before were evaluated in patients with E. coli positive urine cultures (n=24 cultures), 15 of these urethral cultures also had E. coli colonization. There was concordance between urethra and urine cultures concerning the growth of E. coli (P=0.66). CONCLUSIONS: Our study suggested that urethral flora was a significant source for the development of urinary infection in spinal cord-injured patients.

Adult↗
PubMed2002

Surveillance of antimicrobial resistance in gram-negative isolates from intensive care units in Turkey: analysis of data from the last 5 years.

A multicenter antimicrobial surveillance program was established in Turkey in 1995 to monitor the predominant Gram-negative pathogens from intensive care units (ICUs) and antimicrobial resistance patterns of these isolates. Sixteen hospitals participated in the study and a total of 1479 isolates from 1,100 patients were collected. The isolates were tested for their susceptibility against 13 antibiotics by E-test method. Minimum inhibitory concentrations (MICs) for each isolate were determined for imipenem, ceftazidime, ceftazidime-clavulanate, cefoperazone-sulbactam, ceftriaxone, cefepime, cefuroxime, piperacillin-tazobactam, ticarcillin-clavulanate, gentamicin, amikacin and ciprofloxacin. The most common isolates were Pseudomonas spp. (28.2%), Escherichia coli (19.2%) and Klebsiella spp. (19.1%). We found very high resistance rates to all major antibiotics that are used to treat serious infections. Although imipenem is the most active agent, it had an overall susceptibility rate of 68%. Half of the tested Klebsiella spp. strains were found to produce ESBL. This is a very high rate when compared with the literature. Cross-resistance among species was also investigated. 52% of ciprofloxacin-resistant strains were also resistant to imipenem, 80% to ceftazidime, 97% to ceftriaxone, 86% to amikacin and 19% of imipenem-resistant strains were susceptible to ceftazidime and 18% to amikacin. When susceptibilities of the years 1995 and 1999 were compared, the most interesting finding was the decrease in resistance to 3rd generation cephalosporins. In conclusion, this national clinical isolate database shows that resistance rates are high, the change over years is not predictable and continuous surveillance is necessary to monitor antimicrobial resistance and to guide antibacterial therapy.

Anti-Bacterial Agents↗
PubMed2001

The response of isolated anti-HBc positive subjects to recombinant hepatitis B vaccine.

OBJECTIVE: The aim of this study was to evaluate the response to hepatitis B vaccination in isolated anti-HBc positive subjects. PATIENTS AND METHODS: Forty-eight subjects with persistent isolated core antibody were included in the study. Fifty healthy people who were negative for HBsAg, anti-HBs and anti-HBc were included in the study as a control group. They all were vaccinated with recombinant hepatitis B vaccine at 0, 1 and 2 months. RESULTS: Thirty days after each dose of vaccination, serum levels over 10IU/l of anti-HBs are found in 50% of the subjects with isolated anti-HBc after first; in 68.7% after second and in 89.6% after third vaccination. There were no statistical differences between the two groups (P > 0.05). Twenty subjects in isolated anti-HBc group (41.6%) but none of the subjects from the control group responded with a titer of > 50IU/l after 30 days, which suggested an anamnestic response due to prior infection and immunity. Furthermore, 23 subjects in isolated anti-HBc group (47.9%) finally responded after three doses of vaccination (anti-HBs titer > 10IU/l) thus excluding chronic infection and suggesting initial false positive results. CONCLUSIONS: In isolated anti-HBc subjects false positive results (primary response) or prior infection by HBV (anamnestic response) can be detected by anti-HBs response after HBV vaccination.

Adolescent↗
PubMed1998

Lumbar spinal root compression caused by Brucella granuloma.

STUDY DESIGN: A case report of rarely seen extradural brucellosis granuloma causing spinal root compression in the lumbar region. OBJECTIVE: To point out the possibility of extradural compression caused by brucellosis. SUMMARY OF BACKGROUND DATA: Many investigators have indicated that myelopathy or radiculopathy caused by irritation or compression by tiny abscess, disc herniation, or extradural granuloma may occur in brucellosis. Failure to make the correct diagnosis is possible because of the absence of such symptoms of brucellosis as fever, sweating, or fatigue and because findings of physical examination, radiography, and myelography indicate intervertebral disc herniation. METHODS: Review and discussion of the case history are presented. RESULTS: Brucella granuloma compressing the right L5 root and dural sac was diagnosed on computed tomographic scans and was excised subtotally after laminectomy and facetectomy. CONCLUSION: The possibility of extradural compression caused by brucellosis should be considered in endemic areas and must be differentiated from an intervertebral disc herniation by means of agglutination testing and bone scan.

Brucellosis↗
PubMed1993

[In vitro susceptibility to cefoperazone and sulbactam/cefoperazone combination of bacterial strains isolated from various patient materials].

Susceptibility of 110 bacterial strains isolated from clinical materials to Cefoperazone (CPZ) and Sulbactam/Cefoperazone (SBT/CPZ) combination was investigated and every strain was examined for beta-lactamase activity. Total beta-lactamase positivity rate was 40.9%. Antibacterial activity of SBT/CPZ combination was found to be higher than CPZ alone, especially on beta-lactamase producing bacteria.

Bacteria↗
PubMed1993

[Hepatitis B marker seropositivity in prostitutes using ELISA].

In this study, HBsAg, Anti-HBc and Anti-HBs have been investigated in 172 prostitutes and 50 healthy women with ELISA. Anti-HBc seropositivity was increasing with age in prostitutes. No significant difference was found between Hepatitis-B marker seropositivity and working period of prostitutes. In prostitutes, 6.3% HBsAg, 62.7% Anti-HBc, 50.5% Anti-HBs seropositivity and 69.1% total seropositivity was found. Statistically, except HBsAg seropositivity, seropositivity in prostitutes was higher than the control group. Therefore, prostitutes are an important risk group for Hepatitis-B infection.

Adult↗