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Biomedical subjects

O V Baroian

Publications and source records attributed to O V Baroian.

At least 19 recordsLinked to original sources

[Prospective means of decreasing suppurative-septic diseases in puerperae and newborn infants].

The comparative analysis of the occurrence of purulent septic diseases in mothers during the puerperal period and in newborns, observed in a maternity hospital before and after the introduction of the system of keeping newborns together with their mothers, showed a considerable decrease in the morbidity rate among newborn infants (6 times) and in occurrence of mastitis among puerperae (30 times). This is attributed to a decrease in the frequency of the colonization of newborns and mothers in the puerperal period by the hospital strains of staphylococci belonging to epidemic phagotypes. The gradual elimination of staphylococci of phagotype 80, which dominated for several years, from the hospital was observed. To decrease the morbidity rate, the introduction of the system of keeping newborn infants with their mothers in all maternity hospitals of the USSR is proposed.

Carrier State↗

[Role of normal microflora in the treatment of vibrio carrier state in rat gnotobionts].

Materials on the study of interactions between Vibrio cholera El Tor and some indigenous bacteria of human intestinal tract, which proved to be active antagonists in vitro, are presented in this work. Experiments were conducted on gnotobiotic rats (Fisher), using various combinations and variants of the order of the microorganism administration; there were revealed no antagonistic relations between Virbrio cholerae El Tor and Escherichia coli M-17, Lactobacillus fermenti, Lactobacillus plantarum. Vibrio cholera El Tor disappeared completely from the intestinal tract of the rats after its contact with the fecal microflora of healthy rats.

Animals↗

[Model of a chronic Vibrio cholerae carrier based on gnotobiotic rats].

Germ-free monoflora (contaminated with nonpathogenic spore-bearing bacillus) and common albino rats (OFA) were infected with V. cholera El Tor, of Ogava and Inaba serological types (6 milliard microbial cells per 1.5 ml of physiological solution per rat). Approximately one week after the infection the number of vibrios reached hundreds of millions per 1 g of feces and persisted at this level for over 100 days (observation period). Newborn rats were infected by natural way from adult vibrio carriers and also became vibrio-carriers. The number of vibrios excretedby the animals which were germ-free and monoflora before the infection was approximately the same. Cholera vibrios perished completely in the enteric tract and were never revealed in the feces of common (control) rats.

Animals↗