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Biomedical subjects

O V Korovina

Publications and source records attributed to O V Korovina.

At least 19 recordsLinked to original sources

[Bronchoobstructive syndrome in bronchoectasias].

AIM: To specify mechanisms of bronchial obstruction in bronchoectasia (BE). MATERIAL AND METHODS: Clinical, x-ray, bronchological and spirographic examinations with broncholytic test were made in 26 BE patients aged 16-66 years (14 males, 12 females). The membrane-receptor complex of erythrocytes was based on the effect of adrenoantagonist propranolol on osmotic erythrocytic resistance (obsidan test) and effect of adrenoagonist adrenalin on dynamics of ESR. RESULTS: Allergological anamnesis was detected in 69% of BE patients, hereditary allergological anamnesis--in 22%, membrane-receptor changes characteristic for atopic condition by obsidan test--in 46%, fractional erythrocytic sedimentation with adrenalin--in 42%. Bronchoobstruction syndrome occurred in 37% cases with mean values FEV1 46 +/- 6.2%, MSV50 17.4 +/- 3%, MSV75 14.4 +/- 0.9%. The broncholytic test detected a mean increment of FEV1 by 12.2 +/- 3.1%. Latent bronchospasm was revealed in 33% patients with BE. CONCLUSION: The correlation analysis suggests that among mechanisms of bronchial obstruction in bronchoectasia, bronchospasm is of great importance especially in allergological anamnesis pathogenesis of which involves disorders of membrane-receptor complex.

Adolescent↗

[Experience with rovamycin and roxithromycin in patients with chronic bronchitis in the presence of posttuberculous changes].

Rovamycin and roxithromycin were comparatively studied for their effects in 25 patients with chronic bronchitis and posttuberculous changes in the lung. Ten patients received oral rovamycin, 3,000,000 IU, twice daily and 15 had oral roxithromycin, 150 mg, twice daily. The therapy averaged 9 days. Clinical cure was observed in 90% of cases on rovamycin and in 86.7% on roxithromycin. There were no adverse effects of these drugs. The findings suggest that due to their high therapeutical and bacteriological activities, both rovamycin and roxithromycin show their good clinical efficacy in the treatment of exacerbations of chronic bronchitis in patients with residual posttuberculous changes.

Adult↗

[Characteristics of pneumonia in patients with pulmonary tuberculosis].

In healed tuberculosis, pneumonia more frequently arises in the zones of pronounced residual changes. In active tuberculosis combination of tuberculosis with pneumonia often takes place in intact bronchopulmonary segments. Pneumonia in tuberculous patients takes a lingering course in the presence of pneumosclerotic changes in the lungs, tends to acquire bronchial forms, is characterized by slow involution of inflammation, runs atypically in combination of pneumosclerotic changes in the lungs, bronchial stenoses and abnormal cell composition of bronchoalveolar washout. The diagnosis and treatment present difficulties in pneumonia location in the zone of distinct post-tuberculous pneumosclerosis with small segmental lesion. Resolution of inflammatory foci in the lungs in lingering pneumonia may course as long as 8-10 weeks.

Adolescent↗

[Prevalence of post-tuberculous changes in the bronchopulmonary system in the patients with chronic bronchitis].

The prevalence of chronic nonspecific pulmonary diseases was studied in 1880 industrial workers from Russia. The diseases were reported in 26.5% of the examinees. Fluorograms of chronic bronchitis patients indicated residual posttuberculous bronchopulmonary changes in 28.5% of the cases (p < 0.01). By form the bronchitis depended on the variety of the posttuberculous alterations: 76.4% of the asthmatic bronchitis sufferers had minor residual posttuberculous changes (petrifaction of intrathoracic lymph nodes), those with irritative bronchitis had extended posttuberculous changes in 72.7%.

Asthma↗

[The principles of the organization of individualized treatment for bronchial asthma patients].

The authors relate the principles according to which the individualized treatment of bronchial asthma patients may be organized: the permanent treating physician, active participation of the patient in the process of treatment, flexibility of the individualized complex of treatment measures under constant control of the treatment efficacy. Provide the experience gained with such organization of the treatment of 35 patients with grave bronchial asthma ("schools for bronchial asthma patients").

Asthma↗

[Analysis of lethal outcomes in patients with chronic bronchitis].

A study was made of the clinical data and autopsy protocols of 197 persons who died at a hospital of the machine-building plant. Varying bronchopulmonary pathology was discovered in 129 persons, chronic bronchitis in 80 persons. Patients with CB died in the active period of life. Acute pneumonia, cardiovascular diseases and cancer intoxication are among the most frequent causes of death of CB patients. Decompensation of chronic cor pulmonale ranks fourth in frequency, being seen in men engaged in hard physical labour, with concomitant cardial pathology, suffering from chronic alcoholism.

Bronchitis↗

[Status of hemodynamics and its response to exercise in patients with acute pneumonia].

The patients with croupous and focal pneumonia were examined for the response of systemic hemodynamics (HR, SV, MV, BP, PR) to bicycle ergometry in the acute disease period (after temperature normalization, before discharge from hospital and in 6 months following the clinical recovery). Appreciable disorders of the adaptation mechanisms have been demonstrated. They were especially remarkable in the patients with croupous pneumonia and persisted even after 6 months following the patients' discharged from hospital.

Acute Disease↗