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Biomedical subjects

O V Logunov

Publications and source records attributed to O V Logunov.

16 recordsLinked to original sources

[Possibilities and limitations of selective beta 1 adrenergic receptor blockade in clinical practice].

The use of various doses of metoprolol (spesicor, Leiras, Finland), a selective beta 1-adrenoblocker, in patients with CHD combined with clinical or instrumentally detectable symptoms of bronchial asthma or stage I-II essential hypertension with angina pectoris of I-II functional classes, has shown that metoprolol cardioselective blockade is a relative phenomenon which has definite correlation with a dose, duration of therapy, and the initial status of the bronchopulmonary system. An antianginal effect was observed in 68.5% of patients, an antihypertensive effect--in 71.3%, side-effects--in 6.4%.

Adult↗

[Bronchomotor hyperreactivity and bronchial patency in patients with acute pneumonia during clinico-roentgenological convalescence].

A study of bronchial permeability in 98 patients with acute pneumonia during clinico-roentgenological convalescence using a method of the analysis of the flow-volume loop diagram showed disorders of bronchial permeability in 73.46% of the patients, of them obvious disorders in 21.42% and latent ones in 52.04%. Hyperreactivity of the tracheobronchial tree to acetylcholine was established in 84.4% of the patients without signs of obvious obstruction and in some cases only to obsidan indicating the presence of disorders of vagotonic regulation without change in the functioning of beta-adrenoreceptors.

Acetylcholine↗

[Reproducibility of the flow-volume indices of healthy persons and patients with lung diseases].

Reproducibility of the flow-volume indicators at forced expiration and inspiration was calculated during examination of 210 healthy subjects and 420 patients with different pulmonary diseases. Reproducibility of the flow-volume indicators of the median and end part of the forced expiration which reflect largely the function proper of the patency of the distal parts of the bronchial tree was essentially higher in patients and tended toward increase with a rise in the degree of ventilation abnormalities. Reproducibility of the conventional spirographic parameters in healthy subjects and patients with ERF abnormalities did not differ whatever their character and degree.

Adult↗