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O V Paklina

Publications and source records attributed to O V Paklina.

At least 19 recordsLinked to original sources

[Cytologic differential diagnosis of various peripheral lung cancers].

The data on 25 cases of histologically verified bronchioloalveolar carcinoma and papillary adenocarcinoma are discussed. Reliable differential diagnostic cytological features of both diseases were established using a statistical, program and fine-needle biopsy findings. Statistical analysis data pointed to the sets of cytological features: "serial pattern--clear cell boundaries" and "serial pattern--presence of macrovacuoles" as a major factor of accuracy of bronchiolo-alveolar carcinoma and papillary adenocarcinoma diagnosis. These cytological features may be used for reliable diagnosis of the diseases.

Adenocarcinoma, Papillary↗

[Eccrine spiradenoma].

Benign epithelial tumor of the skin--eccrine spiradenoma--is characterized in detail clinically and morphologically.

Adenoma, Sweat Gland↗

[Bronchoalveolar neoplasms].

This review concerns the development and progression of one of the forms of peripheral lung cancer--bronchiolo-alveolar carcinoma (BAC). The study is based on the comparison of roentgenological, histological, immunohistochemical examinations and results of surgical treatment of 482 patients with this tumor. Morphological and clinical variants of BAC are defined. It is confirmed that their biological behavior may vary within the forms and differ from common adenocarcinoma. A close correlation exists between clinicoroentgenological picture and histological form of BAC.

Adenocarcinoma, Bronchiolo-Alveolar↗

[Atypical adenomatous hyperplasia of the lung].

Clinicomorphological analysis was performed in 12 cases of atypical adenomatous hyperplasia of the lung (AAH). This is the proliferative lesion consisting of atypical epithelial cells along the alveolar septa which are found incidentally during pathologic examination of the lung resected because of cancer. We studied morphological and biological characteristics of AAH cells including cytodifferentiation, proliferative activity, tumor-suppressor genes. Our review of the studies of AAH revealed that AAH is alveolar intraepithelial dysplasia and a precursor of lung adenocarcinoma. AAH is an important lesion corresponding to a step in carcinogenesis for peripheral lung adenocarcinomas.

Adenocarcinoma↗

[Endovascular papillary angioendothelioma].

One case of a rare vascular tumor which occurs mainly in the childhood is presented. The tumor has a tendency to recurrence and metastases into the regional lymph nodes in spite of a relatively mature structure.

Hemangioendothelioma↗

[Eccrine mucinous adenocarcinoma].

A case of a rare malignant tumour of the sweat glands is reported. Such tumors are often taken for visceral adenocarcinoma metastasis. The tumor was diagnosed by means of immunohistochemistry.

Adenocarcinoma, Mucinous↗

[Malignant cylindroma].

A case of malignant eccrine cylindroma of the skin studied immunohistochemically is reported.

Carcinoma, Adenoid Cystic↗

[Pagetoid reticulosis].

Pagetoid reticulosis is a rare form of T-cell skin lymphoma. A case of this disease is reported.

Humans↗

[Tumors of the thymus].

Tumours of the thymus include heterogenic group of benign and malignant organ-specific (thymomas and carcinoma) and organ-nonspecific (neuroendocrine, germinogenic tumours, lymphomas and others) neoplasms. Histologic classifications are now the most useful for the correlation with prognosis and clinical manifestations. It is obligatory to do verification of the progression stage.

Carcinoma↗

[Cutaneous pseudolymphomas].

Histological and immunohistochemical characteristics of principal types of skin pseudolymphomas, their differential diagnosis with true skin lymphomas are outlined.

Antigens, Neoplasm↗

[Focal nodular hepatic hyperplasia].

Macroscopic and histological characteristics of focal nodular hyperplasia (FNH) of the liver are presented. Characteristic microscopic signs are the presence of numerous septs with many biliary ducts. Hepatocytes with diploid number of chromosomes show negative Ki-67 and p53. Ultrastructure of hepatocytes in FNH does not differ from that of normal cells of the liver.

Adult↗

[Biliary cystadenoma].

A case of hepatobiliary liver cystadenoma in a 45-year-old female is reported. The tumour looked like a multifocal cyst 18x12x8 cm in size with yellowish content. Inner surface was represented by a column epithelium with nuclei located in the basal part of the cells. Immunohistochemically expression of cytokeratin 19 (similar to the epithelium of bile ducts) was revealed.

Bile Duct Neoplasms↗

[Merkel's cell cancer].

The authors present histological and immunohistochemical characteristics of a rare skin tumor--merkelioma.

Carcinoma, Merkel Cell↗

[Adult hepatoblastoma].

A rare case of hepatoblastoma is reported in a female of 47 years of age with literature review of these tumors in the adults. Microscopically the tumor was represented by the cells of embryonal and fetal types. Immunohistochemically expression of low-molecular cytokeratins as well as that of S-100 protein and hepatocyte antigen was observed.

Biomarkers, Tumor↗

[Classification of pancreatic exocrine tumours].

Current international histologic classification of exocrine pancreatic tumours is presented. Macro- and microscopic characteristics of benign and malignant tumors are described. The role of immunohistochemistry in differential diagnosis is shown.

Diagnosis, Differential↗