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Biomedical subjects

O Watson

Publications and source records attributed to O Watson.

4 recordsLinked to original sources

Troponin T as a first-line test: the Royal Liverpool and Broadgreen University Hospital experience.

Many hospital laboratories are unable to offer a cardiac troponin service because of the cost of providing this assay in addition to existing cardiac enzyme profiles: we circumvented this problem by withdrawing the conventional cardiac enzyme service and substituting cardiac troponin T. By ensuring that only one specimen for cTnT is analysed per episode of chest pain. substantial financial savings have been achieved.

Chemistry, Clinical↗

Soft tissue sarcomas: a ten-year analysis.

Malignant soft tissue tumours are uncommon and the diagnosis is often difficult to make. This study of fifty-nine cases represents a pathological perspective of our experience with these tumours over a 10-year period. Malignant fibrous histiocytoma was the most frequent diagnosis made (36%) and the majority of these occurred in the lower limbs. In 11 (19%) cases, the sarcomas could not be further classified along histogenetic lines. We consider some of the reasons for this and discuss these findings in the light of an increasing trend towards the use of smaller samples for diagnosis.

Adult↗

Clinical experience with prazosin hydrochloride in arterial hypertension.

Of 24 hypertensive patients treated with prazosin hydrochloride, a new vasodilator hypotensive drug with alpha blocking properties, 20 showed a standing blood pressure of less than 140/90 mmHg after six weeks therapy. Five patients had mild, 13 moderate and six severe hypertension. In 11 patients the drug was used alone and in 13 it was combined with thiazides, beta-blockers, clonidine or debrisoquine. Side effects were trivial. Two cases of severe renovascular hypertension responded excellently and one with malignant hypertension is showing a similar good response. The drug can be well combined with thiazides, beta-blockers and clonidine.

Adult↗