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Biomedical subjects

O Wooten

Publications and source records attributed to O Wooten.

6 recordsLinked to original sources
PubMed1982

Ciliary inhibitory effects of asthma patients' sputum.

1. Sputum sols, obtained from patients with chronic obstructive pulmonary diseases, were applied to frogs' isolated palates and the effect on ciliary beat frequency was examined. 2. During clinical exacerbations, a significant number of asthmatic patients produced a distinct, slurry type of sputum, which induced ciliostasis. This ciliary inhibition largely disappeared with clinical improvement, at which time there was also a change of the type of sputum from slurry to mucoid. 3. Samples obtained from normal volunteers and from the great majority of the patients, excluding those with asthma, had no effect on ciliary beating.

Animals↗
PubMed1981

Ciliary beat frequency in human respiratory explants.

Ciliary beat frequency was measured in 60 human bronchial explants obtained by bronchoscopic biopsy. The average rate of beating, at 37 degrees C, was 12.8 +/- 1.3 beats/s, and this rate remained quite constant for periods as long as 4 h. This basic rate of ciliary beat did not seem to be affected by factors such as age, topographical source of the biopsy, underlying disease, smoking history, or chronic alcohol consumption. The values obtained probably represented the "intrinsic" or automatic beat pattern. It remains to be seen if this pattern might be subject to modulation in situ.

Bronchi↗