Biomedical subjects
Odd Mjåland
Publications and source records attributed to Odd Mjåland.
Effects and outcomes after palliative surgical treatment of malignant dysphagia.
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[Inguinal and femoral hernia repair in Norway 1990-2003].
BACKGROUND: The purpose of this study was to chart changes in surgical treatment of inguinal or femoral hernia in Norway from 1990-91 to 1999-2003. METHODS: Data were compiled from the Norwegian Patient Registry based on procedure coding for inguinal and femoral hernia repair. RESULTS: The annual number of femoral hernia repair procedures was constant throughout the study period. From 1990-91 to 2003, the mean age dropped from 66 for both sexes to 63 among men and 62 among women. The female-to-male ratio was constant at 2/1. Emergency admittances went down from 56% to 43% and mean hospitalisation was down from five to four days. The use of mesh repairs increased from 3% (1990-91) to 37% (2003). Incidence rates for inguinal hernia repair increased throughout the period, from 1.8 to 2.3 per 10,000 women and from 20.6 to 32.1 per 10,000 men. Mean age was as down from 63 (both sexes) to 59 among men and 57 among women. The female-to-male ratio remained constant at 1/12. Emergency admittances dropped from 13% to 6%. Mean days of hospitalisation fell from 4 in 1990-91 to 1 in 2003. Two out of three inguinal hernia repairs were done ambulatory in the last year of the study period. The use of mesh repairs increased from 1% in 1990-91 to 78% in 2003. Laparoscopic procedures were rarely used (2% in 2003). INTERPRETATION: In 2003, the majority of inguinal hernia repairs were performed as day surgery with open mesh techniques, in line with European guidelines.
[Regional cerebral perfusion before and after parathyroidectomy].
BACKGROUND: Single photon emission computerised tomography (SPECT) is used to study cerebral blood-flow and cerebral metabolism in various neuropsychiatric disorders. Reduced regional cerebral blood flow has been demonstrated in patients with depression and chronic fatigue, symptoms that are common in primary hyperparathyroidism. The aim of this study was to reveal possible changes in regional cerebral blood flow in patients with primary hyperparathyroidism before and after operative treatment. METHODS: Prospective study of regional cerebral blood flow in 16 consecutive women of median age 72 (range 50-82 years) using SPECT with 99m Tc-labelled hexamethylpropylenamine oxime. The measurements were performed before and two, four and twelve months after parathyroidectomy. The Montgomery and Asberg depression rating scale (MADRS) was used as a parallel clinical test. RESULTS: Reduced (pathological) regional cerebral blood flow was seen before operation in 14 patients, 13 with solitary adenoma and one with double adenoma. After surgery, this improved to normal values in 13, but was further reduced in one. In two patients with preoperative normal regional cerebral blood flow, both of them asymptomatic and with diffuse hyperplasia, a slight reduction was demonstrated. Eight patients had a pathological preoperative MADRS score, which normalised in seven after surgical treatment. CONCLUSION: The finding of reduced regional cerebral blood flow in patients with primary hyperparathyroidism followed by significant improvement after operation might have bearing upon the case for surgical treatment.
[Cholecystectomy in Norway 1990-2002].
BACKGROUND: The purpose of this study was to investigate cholecystectomy incidence and laparoscopy rates in Norway (1990-2002). METHODS: Data were compiled from the Norwegian Patient Registry based on codes for cholecystectomy. RESULTS: From 1990 to 2000-02, age-adjusted incidence rate (per 10,000 inhabitants) for cholecystectomy increased from 2.9 to 4.1 for men and from 7.0 to 11.8 for women. Incidence rates varied between counties. The proportion undergoing laparoscopic surgery increased from 1% in 1990 to 89% in 2000-02. Over the same period the length of postoperative inpatient stay decreased from 7.3 days to 3.3 days. 94% of electively admitted patients were operated by laparoscopic technique in 2000-02. Among patients admitted on an emergency basis, women below 50 were more often operated by laparoscopic technique than older women and men. CONCLUSION: Substantial changes in the treatment of gallstone disease occurred in Norway over the period 1990 -2002. Increased incidence rates for cholecystectomy and reduced length of postoperative inpatient stay were observed after the introduction of cholecystectomy by laparoscopic technique.
[Pain and rehabilitation after inguinal hernia repair in adult male patients].
BACKGROUND: Increased awareness of post-hernia repair pain motivated a study of pain and rehabilitation after day surgery. MATERIAL AND METHODS: Forty male patients were prospectively randomized to conventional (McVay) or open mesh repair. Self-assessment of postoperative pain was based on a four-step verbal scale. Patients and the physicians conducting the study were blinded to the surgical method. Clinical follow-up was performed twice, after four weeks and median 21 months. RESULTS: The open mesh technique generated less pain during the first postoperative week. Chronic light to moderate pain occurred in 20% of patients irrespective of surgical method. A sick leave of one to three weeks was sufficient in 20 out of 27 patients. INTERPRETATION: The study showed no clinical advantage of a tension-free method in terms of rehabilitation and post-hernia repair after the first postoperative week. Because of the relatively high incidence of late treatment-related pain, non-symptomatic adult patients should not be referred for inguinal hernia surgery. The primary sick leave period should not exceed three weeks.
[Internal rectal invagination treated with rectopexy and sigmoid resection].
BACKGROUND: Internal rectal intussusception, usually occurring in women, causes constipation and incomplete evacuation of stool. MATERIALS AND METHODS: Twenty-one women and one man (median age 48) were operated with suture rectopexy and sigmoid resection. The patients were examined with anoscopy and defecography, and symptomatic outcome, patients' satisfaction and morbidity were evaluated. Outcome was based mainly on the validated KESS score for constipation. RESULTS: There was a significant reduction in all ten symptoms. Faecal incontinence improved in the two afflicted patients after operation. The number of patients with constipation was reduced from 20 to 8 (p < 0.01); none became constipated. Mean (95 % CI) colonic transit times in ten constipated patients was reduced from 5.3 (4.1-6.4) to 4.0 (2.6-5.4) days (p = 0.08); seven of these patients had a reduction of transit time as well as constipation score. INTERPRETATION: Rectopexy with sigmoid resection improved symptoms, including constipation and feeling of incomplete rectal emptying.
[Appendicitis and appendectomy in Norway 1990-2001].
BACKGROUND: The purpose of this study was to examine the incidence of appendicitis and appendectomy in Norway from 1990 to 2001. METHODS: Data were compiled from the Norwegian Patient Registry based on ICD-9 and ICD-10 codes for appendicitis and appendectomy. Re-admissions after appendectomy were selected based on institution and allocation numbers for hospitalisation. RESULTS: Age-adjusted incidence rates for appendectomy were 117 per 100 000 for men and 116 per 100 000 for women. Incidence rates were highest among patients aged 10-29. Diagnostic accuracy increased from 81% to 86% in men and from 60% to 71% in women over the study period. Perforation ratio increased from 12% to 21% in men and from 9% to 17% in women. Appendectomy by laparoscopic technique increased during 1998 to 2001 from 5% to 10% of cases for men and from 9% to 15% of cases for women. The proportion of laparoscopic appendectomy was considerably higher in two counties (50% and 28% in 2000-2001). Length of hospital stay was shorter after laparoscopy (median two days) than after open surgery (median three days), with no difference in the rate of re-admission of 4%. INTERPRETATION: Diagnostic accuracy and perforation ratio increased over the 1990s. Patients operated upon with laparoscopic technique had shorter hospital stays and the same re-admission rate compared to patients undergoing conventional surgery. Though the proportion of appendectomies done by laparoscopy doubled from 1998 to 2001, the procedure is not in commonly use in Norway.
[Do-not-resuscitate orders and cardiopulmonary resuscitation at a Norwegian department of surgery].
BACKGROUND: A previous publication indicates a lack of clear guidelines for DNAR orders in Norwegian hospitals. The Norwegian Board of Health has recently published strict requirements for such a procedure. MATERIAL AND METHODS: Patients discharged from a surgical department from 1 March to 31 May 2001 with complicated or advanced cancer and/or a postoperative stay of minimum ten days. The patient files were studied for information on DNAR orders and/or cardiac arrest. RESULTS: 13 out of 69 patients had a DNAR order. In eight of them there was either no explanatory note in the files or no correct signature. Three of the five other patients had taken part in the discussion, so had next-of-kin in two circumstances. Resuscitation was not initiated in any of 14 patients with cardiac arrest. Six of these, who had no DNAR order, all had advanced, inoperable cancer or serious chronic cardiac and respiratory failure. There were no signs that a DNAR order had influenced any other treatment decision. INTERPRETATION: The department had a clear procedure for writing DNAR orders but it was followed in less than half of the cases.
[Secondary anterior sphincteroplasty for anal incontinence after delivery].
BACKGROUND: The prevalence of anal sphincter rupture at vaginal delivery is from 0.5 to 2.5 %. More than 50 % of these patients may need a secondary anterior sphincteroplasty because of anal incontinence. MATERIALS AND METHODS: We present prospective series of 29 women (median age 45 years) operated with an overlapping anterior sphincteroplasty from 1996 to 2001. The patients were examined with anal ultrasonography (n = 23), manometry (n = 19) and neurophysiologically (n = 13), and divided into group 1 (n = 19) with anal sphincter rupture and group 2 (n = 10) with sphincter rupture as well as pudendal neuropathy. All patients (n = 29) were examined with the Cleveland Clinic incontinence score before and median eight (2-64) months after operation. RESULTS: Median incontinence score before and after operation was 11.0 (0-22) versus 5.0 (0-16) (p = 0.002) for group 1; 18.0 (15-24) versus 15.5 (11-24) (p = 0.034) for group 2. There was also a significant difference between the groups concerning incontinence scores both preoperatively (p = 0.045) and postoperatively (p = 0.028). An improvement of continence was seen in 15 (79 %) of the patients in group 1 compared to 4 patients (40 %) in group 2. In group 1 a significant increase of median resting and squeeze pressures was seen. INTERPRETATION: Anterior sphincteroplasty improves anal continence considerably in patients with isolated sphincter rupture. However, patients with evidence of pudendal neuropathy must be informed that they should expect only a minor improvement in continence after operation.
[Localization of parathyroid adenomas].
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Resection rectopexy for internal rectal intussusception reduces constipation and incomplete evacuation of stool.
OBJECTIVE: To study the effect of rectopexy and sigmoid resection (resection rectopexy) on symptoms in patients with internal rectal intussusception. DESIGN: Retrospective and prospective study. SETTING: University hospital, Norway. PATIENTS: 22 patients with internal rectal intussusception. INTERVENTIONS: Resection rectopexy by an open (n = 13) or laparoscopically-assisted (n = 9) technique. MAIN OUTCOME MEASURES: Symptomatic outcome, patients' satisfaction, and morbidity. Outcome was based mainly on the validated KESS score, which covers 10 symptoms included in the definiton of constipation. RESULTS: There was a significant reduction in all 10 symptoms. Two patients complained of incontinence which improved after operation. The number of patients with constipation was reduced from 20 to 8 (p = 0.000) and none became constipated. Mean (95% CI) colonic transit times before and after operation in 10 patients with constipation were 5.3 (4.1 to 6.4) and 4.0 (2.6 to 5.4) days (p = 0.083). Seven of these 10 patients had a reduction of both transit time and constipation score. Six patients had complications after open operations. These included one damaged ureter, reoperations for bleeding, incomplete intestinal obstruction, and 2 wound infections. CONCLUSION: Rectopexy with sigmoid resection resulted in improvement in symptoms, including constipation and feeling of incomplete rectal evacuation, and acceptable morbidity.
[Laparoscopic surgery in Norway].
BACKGROUND: Laparoscopic procedures in gastrointestinal surgery have increasingly been used over the last ten years. This study explores the use of various common laparoscopic procedures in Norway. METHODS: A questionnaire was sent to all 59 public hospitals in Norway in January 1999, of which all but one responded. Laparoscopic surgery was performed in 54 out of 58 hospitals. RESULTS: Most hospitals perform between 11 and 20% of all gastrointestinal operations with laparoscopic technique. Laparoscopic cholecystectomies and anti-reflux surgery have generally replaced open procedures in all hospitals. Appendectomy by the laparoscopic technique accounts for approximately 10% of cases and has become the preferred technique in only one of ten hospitals. Laparoscopic hernia repairs are done in less than 10% of cases. Overall, surgeons' satisfaction with laparoscopy is good and seems slightly higher in district and central hospitals than in university hospitals. Half of all surgical departments plan to use more laparoscopic procedures. INTERPRETATION: Laparoscopic procedures have replaced conventional open surgical procedures for some procedures but is less used than expected ten years ago. A slow and gradual increase may be expected in the years ahead.