Left ventricular pacing lead implantation: potential utility of multimodal image integration.
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Biomedical subjects
Publications and source records attributed to Orly Goitein.
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BACKGROUND: The purpose of this study was to assess the applicability of an annual low-dose computed tomography (CT) screening program for lung cancer in a single institution in Israel, which has a relatively lower prevalence of lung cancer compared with other Western countries, and to examine stage distribution of detected lung cancers. PATIENTS AND METHODS: A cohort of 842 former and current smokers underwent baseline low-dose CT screening and a total of 942 annual repeat screenings over a period of 68 months. The definition of positive results on baseline and repeat screening and their diagnostic workup were guided by the common International Early Lung Cancer Action Program protocol. Recommendations for biopsy of suspicious nodules were based on nodule size, nodule growth, non-resolution following antibiotic therapy, and positron emission tomography scan. RESULTS: The test result was positive in 102 of the 842 baseline screenings (12%) and in 45 of the 942 annual repeat screenings (5%), and biopsy was recommended in 12 baseline and 2 annual screenings. Twelve of the 14 cancers diagnosed (86%) were stage I tumors. CONCLUSION: Our study indicates that the adoption of a common international protocol is feasible, even in a very different clinical setting, yielding a high proportion of early-stage lung cancers.
OBJECTIVE: The purpose of this article is to describe the imaging features of patent ductus arteriosus (PDA) identified on chest MDCT performed for other indications and to describe the additional functional information that cardiac MRI can provide about these lesions. CONCLUSION: The daily use of MDCT studies for the evaluation of pulmonary embolic disease or aortic abnormalities can reveal incidental PDAs. Small incidental PDAs can be identified on chest MDCT angiography timed for either the pulmonary arteries or the aorta. Using multiplanar reformations, one can assess PDA location, caliber, length, and presence of calcifications. The presence of a "positive" or a "negative contrast jet" verifies a patent shunt. Cardiac MRI shows the detailed anatomic and morphologic features of a PDA. Hemodynamic information revealing the presence and severity of a significant shunt is obtainable using velocity-encoded MRI, allowing accurate shunt calculation. Using MDCT and MRI, information regarding the clinical significance of an incidental PDA can influence management decisions. The imaging information was used to determine that one PDA required intervention.
The diagnostic approach to patients who have mediastinal masses should include thorough preoperative imaging. Once limited to plain radiographic techniques, the radiologist now has a wide variety of imaging modalities to aid in the evaluation of the mediastinum. CT is the imaging modality of choice for evaluating a suspected mediastinal mass or a widened mediastinum, and it provides the most useful information for the diagnosis, treatment, and evaluation of postoperative complications.
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An epicardial segment of a coronary artery that courses through the myocardium is termed "myocardial bridging". Generally, this is a benign condition but it may lead to angina, ischemia or infarction. The current diagnostic standard of reference is coronary catheter angiography. Intravascular ultrasound (IVUS) and intracoronary Doppler (ICD) have been recently introduced as well. These are all invasive imaging modalities. We describe the utilization of gated multidetector CT (MDCT) as a non-invasive alternative for diagnosis of this anomaly. Information regarding the tunneled coronary artery including its length, depth, precise location and surrounding myocardium is easily obtainable.