Biomedical subjects

Osamu Kunii

Publications and source records attributed to Osamu Kunii.

3 recordsLinked to original sources

PubMed2003

Associations between nondipping of nocturnal blood pressure decrease and cardiovascular target organ damage in strictly selected community-dwelling normotensives.

BACKGROUND: In hypertensives, nondippers are more likely than dippers to suffer silent, as well as overt, hypertensive target organ damage. In this study, we investigated whether a nondipper status was associated with target organ damage in normotensives. METHODS: We performed ambulatory blood pressure (BP) monitoring, echocardiography, and carotid ultrasonography and measured natriuretic peptides and urinary albumin (UAE) in 74 normotensive subjects with the following criteria: 1) clinical BP <140/90 mm Hg; 2) average 24-h ambulatory BP <125/80 mm Hg. RESULTS: The left ventricular mass index (LVMI) and the relative wall thickness (RWT) measured by echocardiography were greater in nondippers than dippers (LVMI: 103 +/- 26 v 118 +/- 34 g/m(2), P <.05; RWT: 0.38 +/- 0.07 v 0.43 +/- 0.09, P <.01). Plasma atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) were higher in nondippers than dippers (ANP: 14 +/- 10 v 36 +/- 63 pg/mL, P <.01; BNP: 16 +/- 12 v 62 +/- 153 pg/mL, P <.05). There were no significant differences in UAE and intima-media thickness measured by carotid ultrasonography. CONCLUSIONS: Normotensive nondipping may not reflect renal damage, but may have a predominant effect on cardiac damage. Nondipping of nocturnal BP seems to be a determinant of cardiac hypertrophy and remodeling, and may result in a cardiovascular risk independent of ambulatory BP levels in normotensives.

Aged↗

PubMed2003

Home gardening in urban poor communities of the Philippines.

The deficiencies of micronutrients, in particular iron and vitamin A, are common in the Philippines, but their control measures through supplementation and fortification have shown several weaknesses. The present study examines the outcomes of a community-based approach including promotion of home gardening and a diversified dietary practice. A total of 152 mothers in two poor urban communities in Davao City, the Philippines were interviewed with a structured questionnaire. Participants were also asked to keep a brief 7-day self-administered household food record. Focus group discussions were conducted to obtain in-depth information on their attitudes toward home gardening and vegetable consumption. Home garden produce contributed to the diversification of carbohydrate consumed among participants. However, home garden produce reduced the consumption of protein-rich food. There was therefore no discernible improvement in the diets of participants from the consumption of home garden produce. In communities where there was no greengrocer, respondents shared the produce from home gardens. The community-based diet improvement program facilitated home gardening practices, which influenced the dietary practices of the urban poor. The monitoring of food consumption together with community-based programs needs to be expanded in urban poor communities. Our focus group discussion revealed that there was a cognition linking home gardening and vegetable consumption to poverty among some of the participants. More study is necessary on this finding.

Crops, Agricultural↗

PubMedDate not supplied

The 1997 haze disaster in Indonesia: its air quality and health effects.

In this study, the authors assessed air quality and health effects of the 1997 haze disaster in Indonesia. The authors measured carbon monoxide, carbon dioxide, sulfur dioxide, nitrogen dioxide, ozone, particulate matter with diameters less than or equal to 10 microm, inorganic ions, and polycyclic aromatic hydrocarbons. The authors also interviewed 543 people and conducted lung-function tests and determined spirometric values for these individuals. Concentrations of carbon monoxide and particulate matter with diameters less than or equal to 10 microm reached "very unhealthy" and "hazardous" levels, as defined by the Pollution Standards Index. Concentrations of the polycyclic aromatic hydrocarbons were 6-14 times higher than levels in the unaffected area. More than 90% of the respondents had respiratory symptoms, and elderly individuals suffered a serious deterioration of overall health. In multivariate analysis, the authors determined that gender, history of asthma, and frequency of wearing a mask were associated with severity of respiratory problems. The results of our study demonstrate the need for special care of the elderly and for care of those with a history of asthma. In addition, the use of a proper mask may afford protection.

Adult↗