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Biomedical subjects

Osman Baspinar

Publications and source records attributed to Osman Baspinar.

9 recordsLinked to original sources
PubMed2006

Pulmonary arterial pressure in infants with laryngomalacia.

OBJECTIVE: Persistent upper airway obstruction may lead to increased pulmonary arterial pressure in childhood. Laryngomalacia is one of the most common causes of transient upper airway obstruction by laryngeal blockage in infants. The aim of the study is to evaluate the pulmonary arterial pressures in infants with laryngomalacia during infancy period. METHODS: Fifteen infants with laryngomalacia and 30 healthy controls were enrolled into this study. The pulmonary arterial pressures were measured by using Doppler echocardiography. Infants were also evaluated by clinical investigations, telecardiography and electrocardiography. RESULTS: Our results showed that infants with laryngomalacia may have significantly higher pulmonary arterial pressure than healthy subjects. Pressures of patient group were significantly decreased at the end of infancy period. CONCLUSIONS: Increased pulmonary arterial pressure levels due to laryngomalacia are reversible by during developmental process. Therefore, in symptomatic period, evaluation of infants with laryngomalacia by using Doppler echocardiography may be useful for monitoring pulmonary arterial pressure and following up the clinical outcome.

Airway Obstruction↗
PubMed2006

Cardiac index and exercise during VDD/DDD versus VVIR pacing in children. The effects of atrioventricular delay.

Twelve children with a VDD/DDD pacemaker during 100, 125, 150, 200 ms atrioventricular delays and VVIR pacing, cardiac index was measured at rest and evaluated by endurance time during exercise stress test. The optimal atrioventricular delay, which provides highest cardiac index, was 100 ms in three, 125 ms in two, and 150 ms in four and 200 ms in three patients. VDD/DDD pacing with different atrioventricular intervals resulted in a significantly higher cardiac index (6.70 +/- 3.06, 6.49 +/- 2.51, 6.15 +/- 2.35, 6.37 +/- 2.69 l/min/m(2), respectively) than VVIR pacing (5.25 +/- 2.39 l/min/m(2)) at the rest. However, endurance times to treadmill exercise were similar in both the optimal atrioventricular delay (21.6 +/- 3.7 min) and VVIR mode (22.4 +/- 3.4 min) (p > 0.05).

Adolescent↗
PubMed2006

Dobutamine stress echocardiography in the evaluation of cardiac haemodynamics after repair of tetralogy of Fallot in children: negative effects of pulmonary regurgitation.

OBJECTIVE: The aims were to evaluate right and left ventricular systolic function and pulmonary regurgitation (PR) at rest and during dobutamine stress echocardiography (DSE) and to assess relationships between PR and cardiac haemodynamics in late postoperative tetralogy of Fallot patients. METHODS AND RESULTS: Eighteen children (postoperative period 10.9 +/- 2.9 years) had heart rates, PR volumes and velocities, right ventricle (RV) volumes, ejection fraction, cardiac output and index measured at rest and during DSE. Left ventricular ejection fraction did not significantly increase and the RV volumes did not change significantly during DSE (p > 0.05). RV ejection fraction was significantly lower than that of the left ventricle at rest (p < 0.001), and patients failed to increase RV ejection fraction during DSE (p > 0.05). PR measurements increased significantly during DSE (p < 0.05). PR velocity correlated positively with RV end-diastolic volume both at rest and during DSE (p < 0.0 1). PR volume was inversely correlated with ejection fraction, cardiac output and index at rest and during DSE (p < 0.05). CONCLUSION: Latent dysfunction and impaired functional response to stress of both ventricles are detected by DSE. Although many postoperative patients are asymptomatic; assessment of postoperative haemodynamics by exercise or DSE will probably result in early detection of latent ventricular dysfunction.

Adolescent↗
PubMed2005

Long tortuous aorta in a child with Larsen syndrome.

A three-year-old boy with unusually flattened facies, multiple joint dislocations and eye abnormalities suggesting the presence of Larsen syndrome presented with a broad mediastinum on routine chest radiography. Computed tomography revealed a huge dilated tortuous aortic arch. Transthoracic echocardiography demonstrated aortic valve dilation, aneurysmal dilation of the ascending aorta with a high aortic arch and a kink in the arch at the isthmus level. Aortography showed a dilated elongated aorta with two acute curves, one at the ductal level and the second at the diaphragmatic level. These aortic lesions may have prognostic significance for the future risk of rupture or dissection. The present article reports the presence of a tortuous aorta in a child with Larsen syndrome.

Abnormalities, Multiple↗
PubMedDate not supplied

Pulmonary arterial pressure in children with allergic rhinitis.

BACKGROUND: Chronic upper airway obstruction may lead to increased pulmonary arterial pressure in childhood. Allergic rhinitis is one of the frequent causes of upper airway obstruction by nasal blockage. The aims of the study were to evaluate the pulmonary arterial pressures in children with allergic rhinitis and the effect of topical corticosteroid therapy. METHODS: Forty-nine children composed of 27 subjects with seasonal and 22 subjects with perennial allergic rhinitis were enrolled in this study. The pulmonary arterial pressures were measured by using Doppler echocardiography. RESULTS: The pretreatment pulmonary arterial systolic, mean, and diastolic pressures of study group were significantly higher than in healthy controls (p < 0.05). The pulmonary arterial systolic and mean pressures of the patient group significantly decreased at the end of study (p < 0.05), whereas the decrease of the diastolic pressure was not statistically significant (p > 0.05) after the treatment of a topical corticosteroid, mometasone furoate (100 microg per day), for 8 weeks. CONCLUSION: Our results showed that children with allergic rhinitis have higher pulmonary arterial pressure levels compared with healthy controls and that increased pulmonary arterial pressure levels due to allergic rhinitis are reversible by using nasal topical corticosteroids. Further studies are needed to determine the clinical aspect of increased pulmonary arterial pressure.

Anti-Allergic Agents↗