Lactation, galactorrhea, and timing of reduction mammaplasty.
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Female↗
Biomedical subjects
Ozlem Gundeslioglu
Publications and source records attributed to Ozlem Gundeslioglu.
Low incidence of mamographically detected microcalcification in breast cancer patients with lobular histology may be attributed to low levels of osteopontin.
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Breast Neoplasms↗
Adjuvant trastuzumab use in high-risk breast cancer patients may prevent development of contralateral estrogen receptor-negative breast tumors.
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Antibodies, Monoclonal↗
Neoadjuvant chemotherapy with weekly paclitaxel in breast cancer patients may increase release of cancer cells into circulation by decreasing interstitial fluid pressure.
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Antineoplastic Agents, Phytogenic↗
Increased cabbage intake may inhibit metastatic and invasive capacity of breast cancer cells by inhibiting CXCL12(SDF-1 alpha)/CXCR4.
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Antineoplastic Agents↗
Human papilloma virus and breast cancer.
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Breast Neoplasms↗
Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients.
Recently, cyclooxygenase-2 (COX-2) inhibitor therapy has emerged as a possible new approach to the prevention and treatment of colorectal cancer (CRC). The COX enzymes (COX-1 and COX-2) are key enzymes of prostaglandin (PG) biosynthesis and are overexpressed in approximately 80% of human CRCs. Presumably, bioactive lipid products of COX, such as PGE(2), are responsible for some of the pro-neoplastic effects mediated by this enzyme. The early effects of COX-2-derived PGE(2) are in part mediated by the epidermal growth factor receptor (EGFR). Selenomethionine decreases COX-2 protein and PGE(2) levels. Cetuximab is a chimeric IgG1 monoclonal antibody that binds to EGFR with high specificity thus blocking ligand-induced phosphorylation of EGFR. Cetuximab has clinically significant activity when given alone or in combination with irinotecan in patients with irinotecan-refractory CRC. We suggest that selenium supplementation by decreasing the COX-2 protein and PGE-2 levels in cancer cells may increase efficacy of cetuximab in advanced CRC patients.
Adenocarcinoma↗
Closure of large scalp defects by modified Gillies triple scalp flaps in patients with scalp tumors.
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Female↗
Nanobacteria and breast implant capsule contracture and calcification: a hypothesis.
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Breast↗