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Biomedical subjects

P A Addy

Publications and source records attributed to P A Addy.

6 recordsLinked to original sources
PubMed1978

Jaundice and infectious mononucleosis in Ghana.

A total of 715 sera from jaundiced cases were examined for Infectious Mononucleosis (IM) antibodies and 5.03% were found to be positive. It was further found that the incidence of IM antibodies in the study population increased with age, the incidence being most prevalent amongst the 11-20 year age-group. IM antibodies with jaundice were found to be most prevalent in the Volta and Eastern Regions, i.e. amongst populations of the coastal-lowland-swampy-shrubland zone of the country, particularly during the dry season which stretches from October through March. A preponderance of IM antibodies amongst females of the age-group 11-20 years was recorded. The possible mode of IM transmission in the tropical setting, with particular reference to Ghana, is proposed.

Adolescent↗
PubMed1978

Hepatitis Bs antigen, antigen subtypes and hepatitis Bs antibody in Ghana.

In a study on the prevalence of hepatitis Bs antigen and antibody in 374 Ghanaian patients, 305 of whom had hepatic diseases and sixty-nine with non-hepatic diseases, it was found that Bs antigenaemia and antibody rates were, respectively. 38.7% and 4.3% in patients with hepatic diseases. In patients with non-hepatic diseases the corresponding values were 14.5% and 10.1% respectively. It was further found that both antigenaemia and antibody rates were higher in females than in males with hepatic diseases. However, HBs antigenaemia was highest in male children aged 0-5 years with hepatic disease than in their female counterparts. The antigenaemia rate was highest among both sexes in the 11-20 year age group. No antibody was detected in both male and female patients aged 6-10 years. Hepatitis Bs antigen was detected in all seven regions of the nine in the country surveyed. On the other hand, HBs antibody was detected in patients with hepatic diseases as well as in those with non-hepatic diseases in all the seven regions surveyed except in the Eastern Region. The only subtype detected in the survey was ayw.

Adolescent↗
PubMed1978

Vaccines and vaccinations in the under-fives in Ghana, a tropical developing country.

In this paper, an attempt has been made to focus attention on the important childhood killer but immunizable diseases in Ghana, giving where available morbidity and mortality figures. Immunization schedules currently adopted in Ghana are discussed in the light of immunological considerations, the half-life of acquired maternal antibodies and from the point of view of known epidemiological patterns of these immunizable diseases. An attempt was thus made to justify the adoption of the immunization schedules currently in force in Ghana. Problems relating to some of the vaccines used in immunization of the under-fives in Ghana have been discussed in the light of personal experiences and the experiences of other colleagues, giving--where possible--suggestions for improvement. Finally, the paper delineates problem areas in immunization programmes of the under-fives in Ghana.

Bacterial Vaccines↗
PubMed1975

Seroimmunity of adult Ghanian hospital staff and their wards to poliomyelitis.

The antibody content of sera collected from 104 adult staff of the Korle Bu Teaching Hospital and 16 of their wards were studied by microtitre neutralization test to poliovirus types 1, 2 and 3. The immune status of the study population was highly satisfactory; there was only one (0.83%) out of the 120 persons studied without antibodies to all three poliovirus types. The percentage of sero-positive subjects to the individual poliovirus types, that is 1, 2 and 3 were 75.83%, 70.00% and 86.16% of the study population. Immunity in relation to age was also studied.

Adolescent↗