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Biomedical subjects

P A Buchard

Publications and source records attributed to P A Buchard.

10 recordsLinked to original sources

[Can we still give a fibromyalgia diagnosis?].

This article is an attempt at a critical analysis of the fibromyalgia concept. The author applies himself to describing how the profile of this syndrome, associating chronic widespread pain to allodynia, became more and more precise, until it obtained the status of disease. He emphasizes that the concept lost its initial meaning when the criteria, resulting from an ambitious scientific methodology, were used to establish a diagnosis on an individual scale. He comes to the conclusion that after a century of existence, fibromyalgia does not possess any specific quality that would distinguish it from other chronic widespread pain syndromes to make it a pure nosological entity. It is an artificial construct that adds nothing to the understanding of a pain phenomenon and allows no rational therapeutic approach.

Fibromyalgia↗

[Polymyalgia rheumatica and pulmonary cancer: paraneoplastic syndrome].

An 83-year-old lady was admitted for bilateral pain and weakness of the shoulder and hip girdles. These symptoms suggested a Polymyalgia rheumatica (PMR) but there was no response to corticosteroids. A pulmonary adenocarcinoma without any metastasis was then diagnosed. The excision of this tumor was followed by prompt and complete recovery. The erythrocyte sedimentation rate became normal within a few days, also. Such an issue seems to prove that PMR may occasionally be associated with neoplasia. This association appears anecdotal in the literature and remains without clear explanation.

Aged↗

[Fractures due to bony insufficiency of the sacrum].

Six cases of insufficiency fracture of the sacrum were diagnosed in the Rheumatic Diseases Division of the CHUV during 1990. They show that this recently described entity is frequent. Present knowledge of the clinical course, predisposing factors, radiological findings and treatment is reviewed. This diagnosis should be considered in all cases of lower back pain occurring in postmenopausal women. Awareness of this entity should make it possible to avoid unnecessary invasive investigations.

Aged↗

[Comparison of fructosamine and Hba1c for the evaluation of metabolic control of diabetic patients].

Fructosamine values, and the influence thereon of age, BMI and sex, were determined in 384 nondiabetic individuals aged between 20 and 95 years. In this control group mean F levels were 2.45 +/- 0.25 mmol/l and were age-related only, rising from 2.3 in the second decade to 2.6 in the eighth. We compared F and HbA1c in 135 diabetic patients. F correlated with HbA1c in the diabetic group (r = 0.76, p less than 0.001). Because of its biological properties fructosamine could become a useful pointer in the metabolic follow-up of diabetic patients, especially where clinic visits are frequent.

Adult↗