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P A Harrison

Publications and source records attributed to P A Harrison.

25 records · Page 2Linked to original sources

Brief Minnesota Multiphasic Personality Inventory scales to screen for substance abuse.

Research has focused on development of accurate screening instruments to detect alcoholism. The Minnesota Multiphasic Personality Inventory (MMPI) has long been employed, but the utility of previous scales in differentiating substance abusers from normals remains unclear. Conley and Kammeier (J. Consult. Clin. Psychol., 48 (1980) 665) identified seven MMPI items which appeared to be specific to alcoholism. In a replication attempt, this study compared MMPI's for 1403 male and 323 female job applicants and 228 male and 76 female chemical dependency inpatients. MMPI items were chosen through empirical identification of those with greatest endorsement differences. A 13-item scale emerged with an endorsement differential exceeding 45%. Four of the seven Conley-Kammeier items replicated in the 13-item scale. These shorter MMPI scales appear superior to the older 50-item-plus MacAndrew and Holmes scales for screening normal populations, providing cutting scores which yield specificity exceeding 80% with sensitivity greater than 90%. However, results must be interpreted with caution, and limitations regarding the state of the art are set forth.

Alcoholism↗

Multidimensional impact of treatment for substance abuse.

The establishment of a multi-facility patient registry system has facilitated the routine documentation of problems associated with substance abuse. The comparison of information on 1,020 adult inpatients from the six-month period before and the six-month and twelve-month periods after treatment is reported. The multidimensional approach to program evaluation suggests significant economic impact of inpatient treatment on vocational functioning, health care demands, and arrests. Treatment for alcohol and other substance abuse appears to have an extremely significant potential for economic payback to local, state and federal governments, insurance providers, corrections agencies, private industry, and, of course, patients and their families.

Adult↗

Alcoholics anonymous after treatment: attendance and abstinence.

Follow-up data on 900 inpatients at eight hospital-based chemical dependency treatment centers demonstrate a high correlation between total abstinence 6 months after discharge and weekly attendance at Alcoholics Anonymous during this period. Almost three-fourths (73%) of the regular attendees remained chemically free, compared with one-third (33%) of the nonattendees. These data suggest that Alcoholics Anonymous is an appropriate and beneficial aftercare for the majority of treatment inpatients.

Adult↗

Two-Dimensional Electrophoretic Mapping of Proteins of Bundle Sheath and Mesophyll Cells of the C(4) Grass Digitaria sanguinalis (L.) Scop. (Crabgrass).

Two-dimensional electrophoresis was performed on proteins of bundle sheath and mesophyll cells isolated from the C(4) grass Digitaria sanguinalis (L.) Scop. Two-dimensional maps of these proteins were constructed and ribulose-1,5-biphosphate carboxylase and phosphoenolpyruvate carboxylase were identified. Of the total number of proteins found in both cell types, 36% were found only in bundle sheath cells, 17% only in mesophyll cells, and 47% in both cell types. By comparison, the distributions of 48 enzymes assayed in these cell types were 35%, 21%, and 44%, respectively.Protein patterns were also compared with C(4) plants exhibiting different decarboxylation pathways and, in both bundle sheath and mesophyll cells, proteins were found which were unique to each species. Bundle sheath proteins of one C(4) species were found to be more like bundle sheath proteins of another C(4) species than like mesophyll proteins of the same species.

Journal Article↗