PubMed Health⌕ Search

Biomedical subjects

P A MILLER

Publications and source records attributed to P A MILLER.

At least 19 recordsLinked to original sources

ETHYLATION: BIOLOGICAL FORMATION OF AN S-ETHYL HOMOLOG OF LINCOMYCIN.

Streptomyces umbrinus var. cyaneoniger produces the antibiotic lincomycin. When grown in the presence of ethionine an additional antibiotic is produced. Physical and chemical analyses and incorporation of radioisotopes indicate that the new antibiotic is the S-ethyl homolog of lincomycin.

Amino Acids↗

FORMATION OF "PROTOPLASTS" OF STAPHYLOCOCCUS AUREUS WITH A FUNGAL N-ACETYLHEXOSAMINIDASE.

Hash, John H. (Lederle Laboratories, Pearl River, N.Y.), Marcia Wishnick, and Philip A. Miller. Formation of "protoplasts" of Staphylococcus aureus with a fungal N-acetylhexosaminidase. J. Bacteriol. 87:432-437. 1964.-"Protoplasts" of Staphylococcus aureus were obtained when cells were treated with a fungal N-acetyl-hexosaminidase in hypertonic sucrose solution. The "protoplasts" were sensitive to osmotic shock, and were free of amino sugars and rigid cell walls. They were unable to regenerate cell walls and form colonies. They may be true protoplasts. Osmotic barriers in the "protoplasts" were preserved, and the "protoplasts" incorporated C(14)-l-alanine at about 60% of the rate of intact cells.

Alanine↗