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Biomedical subjects

P A Temin

Publications and source records attributed to P A Temin.

At least 19 recordsLinked to original sources
PubMed1994

[The enkorat treatment of infantile spasms and the Lennox-Gastaut syndrome].

The drug encorat, an analogue of valproic acid (Sun, India) was given to 16 children aged from 4 month to 5 years suffering from resistant forms of early infantile epilepsy. Twelve of them had infantile spasms, four Lennox-Gastaut syndrome. The treatment produced good results in 75% of the patients. Encorat mono- or polychemotherapy is able to discontinue or decrease the frequency of the epileptic fits, improve the patients' condition in resistant early childhood epilepsy.

Anticonvulsants↗
PubMed1993

[Temporal-lobe epilepsy with psychosensory and gustatory attacks].

A variety of temporal epilepsy that manifested by paroxysms in the form of psychosensory and gustatory ones is described. A 20-year-old man was placed under observation. Since 14 years of age he demonstrated attack-like conditions with a sensation of the pushing apart and swelling in the head, of an increase of the head size, and unpleasant sickly sweet taste in the mouth. The attacks were accompanied by anxiety and general weakness. Neurological examination revealed left-handed hemisymptomatology, EEG demonstrated activity prevailing in the occipitotemporal leads on the right. The neuropsychological findings attested to the impairment of the structures of the right temporal lobe. Analysis of the clinical manifestations of epilepsy, of the neurological findings, and the neuropsychologist's conclusion made it possible to suggest the site of the epileptic focus in the field of the hippocamp on the right.

Adult↗
PubMed1992

[Infantile facioscapulohumeral muscular dystrophy].

The authors describe a 16-year-old patient suffering from facial scapulohumeral myopathy. The given case is regarded as sporadic. The disease was characterized by an early debut and rapid progression of neuromuscular disorders. Marked myasthenia and muscular atrophy of the face, shoulders, thighs, as well as contractures in the knee joints, hands and feet were noted. By 15 years the patient demonstrated a noticeable progress of motor disorders: she was unable to stand up from the chair, experienced difficulties in walking along the ward, and had a waddle gait. The given symptom-complex corresponds with the infantile variety of facial scapulohumeral myodystrophy.

Adolescent↗
PubMed1992

[The effect of osteochin on the dynamics of the course of the myodystrophic process].

Osteochin (Quinoin, Hungary) efficacy was studied in the treatment of 20 patients with Duchenne's progressive myodystrophy. The drug was administered in a dose of 200 mg a day for a month. A favorable effect of such therapy was observed in all the patients. Osteochin was found to have a correcting effect on Ca-regulating hormone function and to promote stabilization of the myodystrophic process.

24,25-Dihydroxyvitamin D 3↗
PubMed1991

[A benign variant of the course of Duchenne muscular dystrophy in a child with short stature].

The authors describe a case of a benign variety of progressive Duchenne type muscular dystrophy in a 8-year-old short-stature boy. Provide the electromyographic and electroneuromyographic data, measurements of the growth hormone in blood serum and osseous age. Make suggestions about coupled inheritance of progressive Duchenne type muscular dystrophy and short stature . The latter one is likely to be attended by a decrease of anabolic processes, which may determine a more benign course of the myodystrophic process.

Child↗
PubMed1991

[Congenital autosomal-recessive familial spastic paraplegia].

The authors describe a family living in the Dagestan where three relative sibs, girls, suffered from familial spastic paraplegia. The variety described is marked by early debut, pronounced intrafamilial polymorphism of the disease course, autosomal recessive type of inheritance which, according to the reported data, is marked by frequently occurring combination with damage to other organs and systems (the familial spastic paraplegia "plus"). The "pure" disease variety seen in autosomal recessive type of inheritance, detection of the disease symptoms since the birth indicate that the case in question is a rare clinical variety of familial spastic paraplegia.

Child↗
PubMed1991

[Effect of testenate in the treatment of epilepsy in men].

The paper is concerned with the mechanisms of the effect of hormones on convulsive preparedness of the brain. A study was made of the effect of the androgenous hormonal drug testenat on the clinical course of epilepsy. Testenat was found to be an effective drug decreasing the rate of epileptic seizures, transforming generalized convulsive attacks to partial, reducing the gravity and duration of the ++post-paroxysmal period. The mechanisms by which testenat affects the bioelectric activity of the brain at the cellular level are under discussion.

Adult↗
PubMed1991

[Sex disorders in men with epilepsy].

The authors depict the character of sexual disturbances in 108 men suffering from epilepsy. The epileptic men demonstrated diverse sexual disturbances which manifested in hyposexuality (46.7%), hypersexuality (2.9%), and ejaculation disorders (9.5%). Fertility and the marital status were found to be lowered in the patients with hyposexuality. The highest incidence of hyposexuality was recorded in a group of patients with temporal epilepsy and in those given lasting treatment with anticonvulsants.

Adult↗
PubMed1991

[Rapidly progressing facio-scapulo-humero-femoro-peroneal muscular dystrophy with sensorineural deafness].

The paper concerns a family in which father and sibs (two brothers and a sister) suffered from rapid-progressing myodystrophy. Clinically, the disease was marked by a debut in the pubertal period (at 12 to 13 years), derangement of the muscles of the limb girdles, proximal parts of the legs and arms, and distal parts of the legs. The given case was also characterized by the impairment of the cervical and facial muscles as well as by associated neuromuscular lesions and neurosensory hypoacusis. The case described supports the clinical pleomorphism of the facial scapulohumeral form of Landouzy-Dejerine myopathy.

Adolescent↗