PubMed HealthSearch

Biomedical subjects

P A Thornton

Publications and source records attributed to P A Thornton.

14 recordsLinked to original sources

Nutritional assessment of the hospitalized patient.

While some symptoms of the malnourished state are obvious, others may be subtle. In either case, assessment is indicated to uncover any inconspicuous symptoms and secondly to quantitate those that are apparent. Such procedures are pertinent because immune competence and other organ systems related to survival are dependent on the adequately nourished state. It is also important to remember that certain vitamin and mineral deficiencies may accompany protein calorie malnutrition and thus their attention would be especially needed during the repair of this condition. The deficiencies seen most often include vitamins C, A, and D, as well as zinc, copper, and calcium. Furthermore, the refeeding process may also precipitate shortages of potassium, phosphate, and magnesium, unless adequate amounts of these nutrients are included in the diet. From this and earlier discussed situations, it is suggested that nutritional assessment should be the initial step in nutritional therapy. It should be approached with concern not only for what the collective assessment tools will reveal, but also with consideration for the patient's clinical problem, the current metabolic situation and the projected therapeutic regimen which will be formulated.

Body Weight

Hypocalcemic development in high and low calcium-adapted chicks during acute calcium deficiency.

Chickens were adapted to either a high or low calcium intake and then subjected to an acute calcium deficiency by feeding ground yellow corn +/- phosphate. Hypocalcemia developed within 3-5 h in those chicks given the corn plus phosphate. The response was about equal in the high and low adapted animals suggesting that the effect was not mediated via regulatory factors such as parathyroid hormone or thyrocalcitonin intervention. Rather, it is suggested that the influence of phosphate is direct and may be due to an enhancement of calcium movement from the fluids to the bone. The high calcium adapted chicks also exhibited some hypocalcemia in response to eating corn without phosphate supplementation. This development, contrary to the other cases, appeared to be due to a lag in calcium regulating mechanisms. The low calcium adaptation did not seem to influence growth within the timespan used, but there was a significant reduction in bone ash values and of adrenal enlargement. Thus, it was evident that the low and high calcium diets were different in regards to calcium metabolism and it appears that the low calcium intake may have been stressful.

Adaptation, Physiological