PubMed HealthSearch

Biomedical subjects

P Agger

Publications and source records attributed to P Agger.

5 recordsLinked to original sources

Urological septicemia. A retrospective study.

In order to investigate the clinical course and outcome of septicemia in urological patients, data were collected retrospectively from all patients admitted to a specialized urological department, in whom positive blood cultures were drawn. During a 5-year period 91 patients were registered with urosepsis corresponding to an incidence of 1.2%. In non-iatrogenic urosepsis due to ureteral obstruction women dominated over men, however, in iatrogenic disease--after investigative manoeuvres as well as after surgery--men by large dominated the material. Gram-negative bacteria were responsible for almost 75% of the septicemias and for 99% of the cases where septic shock was present. Where a urinary infection was demonstrated prior to septicemia (45%- identical bacteria were subsequently found in the blood, whether the focus had been successfully treated or not. Septic shock developed in 20 of the patients of whom 3 died. This overall mortality of 3% occurred only in patients with comcomitant serious disease. In general the course of septicemia was benign and the complication rate low. It is concluded that in urological patients septicemia is a less serious problem than in gastroenterological patients. The possible explanation for this is discussed in relation to the more discrete diagnostic and therapeutical procedures in the urological clinic.

Adult

Quantitative evaluation of testicular biopsies in varicocele.

Testicular biopsies from 81 patients with varicocele were evaluated by the score count method. Thirty-two patients sought treatment for infertility. Bilateral biopsies were performed in 47. Spermatogenesis was generally reduced in patients with varicocele, but there was no difference between the right and left tests. The testicular biopsy mean score correlated significantly with the total sperm count. There was no correlation between the size of the varicocele and the reduction in spermatogenesis. Although varicocele is nearly always left-sided, its mechanism of action must involve both testes. This mechanism is still unknown.

Adolescent

Quantitative evaluation of testicular biopsies before and after operation for varicocele.

Testicular biopsies and semen samples were examined before and approximately 1 year after operation for varicocele in 39 men. Two men were excluded because of Sertoli-cell-only syndrome. Of the remaining 37, 22 were operated upon for infertility. The testicular biopsies were quantitated with the score count method. The operation for varicocele significantly improved the testicular tissue. THe numbers of tubuli obtaining a high score increased and the biopsy mean scores also increased significantly. However, few testes became perfectly normal. The duration or the size of the varicocele apparently has little effect upon the state of the testicular tissue or the change in it after operation.

Adult

Does the oesophageal balloon compress oesophageal varices?

The pressure transmitted to the oesophageal wall was measured in 3 patients with bleeding oesophageal varices controlled by balloon tamponade. The pressure transmitted was considerably lower than the pressure inflated, and all patients suffered retrosternal pain when the transmitted pressure rose to 40 mm Hg. Furthermore, the diameters of oesophageal balloons of 23 Sengstaken-Blakemore tubes (Rüsch) were measured at increasing inflation pressure. The compliance was very high. All balloons bulged at median inflation pressures of 75 mm Hg, and the pressures fell to a median of 55 mm Hg unaffected by further inflations. The diameter at 40 mmHg was 27.3 mm. In the light of these observations it remains still to be explained how the oesophageal balloon of the Sengstaken-Blakemore tube effects haemostasis in bleeding oesophageal varices.

Esophageal and Gastric Varices