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Biomedical subjects

P Althaus

Publications and source records attributed to P Althaus.

At least 19 recordsLinked to original sources

[Sarcomatoid carcinoma of the bladder in a 25-year-old man].

A 25-year-old patient with a rapidly growing sarcomatoid carcinoma of the urinary bladder is reported. The diagnosis was made on the basis of extended atypical proliferations of spindle or pleomorphic cells in the area of pelvic floor and the radix of the penis. The tumor showed invasion of the blood and a high Ki-67 growth fraction up to 40%. Immunohistochemically, the reactions with antibodies against cytokeratin, EMA, and vimentin were positive, while negative results were obtained in reactions with antibodies against desmin, actin, PSA, S 100, human epithelial antigen (Ber-EP4), and cytokeratin 13. The differential diagnosis against myosarcomas, pseudosarcomatous lesions, and inflammatory pseudotumours is discussed. After radical surgery a pelvic recurrence and pulmonary metastases developed, which led to the patient's death 3 months later. This case shows that sarcomatoid carcinomas of the urinary bladder can be found even in young people.

Adult↗

Renal autotransplantation for idiopathic retroperitoneal fibrosis.

Extensive loss of the ureter is a potential complication of surgery performed to relieve ureteral obstruction caused by retroperitoneal fibrosis. The authors describe the twelfth case managed successfully by renal auto-transplantation and review the literature.

Humans↗

[Histologic changes after laser treatment of superficial penis tumors].

In the last years the excision of superficial benign and malignant penile tumors by laser surgery has been well established. Our first experience confirm the excellent cosmetic and functional results after laser surgery. Furthermore a decrease of recurrence rate was found due to laser vaporization of the adjacent tumor area. In spite of tissue damage by histological examination we were able to classify benign and malignant findings.

Adolescent↗

[ESWL with the Lithostar--experience with 3,000 treatments].

The experiences with 3,000 extracorporeal shock wave lithotripsies of kidney and ureteral calculi using the Lithostar are reported. Indications, contraindications and therapeutic approach are reviewed and the importance of out-patient follow-up is stressed. The success rate of 75% (including further spontaneous passage of residual desintegrated calculi) is good in the view of an unselected and unfavourable patient population. In the other patients a second ESWL treatment may be necessary. In the initial period in 6% of the patients percutaneous nephrolitholapaxy or open operation have been performed whereas in the last 100 patients it was not necessary.

Adolescent↗

[The use of imaging procedures following kidney transplantation--diagnostic strategy].

Despite the continuously increasing number of successfully transplanted kidneys, graft and patient are still "threatened" by several postoperative complications as acute and chronic rejection, acute tubular necrosis, urologic and vascular complications and disorders caused by immunosuppressive medication. An early and safe detection of these conditions is of high clinical importance and a challenge to diagnostic imaging. All radiologic methods and nuclear medicine have their value for transplantation diagnostics, but in recent years a trend to noninvasive methods with no contrast media and little discomfort to the patient is clearly visible (sonography, magnetic resonance). Rational diagnostic strategies for various conditions after renal transplantation are described.

Diagnostic Imaging↗

[CT and MRT--their influence on urology].

Generally it can be concluded, that according to our present knowledge MRT is superior to CT only for the staging of muscle infiltrating cystic carcinoma and prostatic carcinoma. New possible prospects are MRT and spectroscopic investigations for renal transplants.

Humans↗

[Clinical experiences in 210 percutaneous removal of kidney and ureteral calculi].

The introduction of percutaneous nephrolithotomy and ureterolithotomy has greatly widened the therapeutical spectrum of urolithiasis. In this paper indications and contraindications of percutaneous stone removal will be discussed as well as techniques of this procedure. 210 percutaneous stone operations were performed after an initial training period primarily using local anesthesia (neuroleptanalgesia). This operative procedure allowed stone removal in patients otherwise inoperable because of increased operation risk or of advanced age. With increasing experience the success rate has been improved, though the stage of difficulties in nephrolithotomy and ureterolithotomy has increased too. Percutaneous operation primarily in connection with extracorporal shock wave lithotripsy is the first treatment modality for patients with staghorn stones. Possible complications (bleeding, perforation, injury to neighbouring organs) and their treatment are discussed.

Adolescent↗

Testicular autotransplantation for intraperitoneal cryptorchidism in childhood. A case against neglecting the venous anastomosis.

A case of autotransplantation of an intra-abdominal testis into the scrotum in a 9-year-old boy using a microsurgical technique without venous anastomosis is described in detail. The operation failed subsequently due to venous outflow obstruction and the testis underwent atrophy 6 months postoperatively. It was suggested that both the arterial and venous anastomoses may be necessary for the management of this difficult surgical problem.

Anastomosis, Surgical↗