PubMed Health⌕ Search

Biomedical subjects

P Altidis

Publications and source records attributed to P Altidis.

4 recordsLinked to original sources
PubMed2000

Spontaneous otoacoustic emissions in neonates and effect of contralateral white noise stimulation.

Neonates younger than the age of 12 weeks (10 full-term, 20 preterm) had an audiological assessment consisting of brainstem audiometry, tympanometry, transiently evoked otoacoustic emissions, and spontaneous otoacoustic emissions with contralateral white noise stimulation. Results from brainstem audiometry, tympanometry, and transiently evoked otoacoustic emissions suggested normal middle ear function and normal cochlear function. All full-term neonates had multiple spontaneous otoacoustic emissions, and contralateral white noise stimulation resulted in enhancement of emissions in 80%, whereas in 20% the emissions were suppressed. In preterm neonates, spontaneous otoacoustic emissions were present in 55%. These emissions were mostly solitary and, in 64%, showed suppression with contralateral white noise stimulation. Embryological data taken into consideration suggest that the pattern of spontaneous otoacoustic emissions in preterm neonates is more likely related to immaturity of the central auditory pathway rather than the cochlea.

Acoustic Stimulation↗
PubMed1999

Stress electrocochleography.

Electrocochleographic recordings after changes of middle-ear and intracranial pressure were studied in a group of otologically normal subjects and in patients with suspected Ménière's disease. Electrocochleography performed under these conditions was called stress electrocochleography. It was useful to distinguish among Ménière's disease, benign positional vertigo, and a round-window fistula. Changes of middle-ear pressure, whether positive or negative, always resulted in a rise of the SP/AP ratio. Raised intracranial pressure after Trendelenburg positioning showed fluctuations of the SP/AP ratio in both normal subjects and symptomatic patients. However, in normal subjects, a congruent pattern of these fluctuations was apparent, whereas symptomatic patients exhibited a discordant pattern. The discordant pattern, typical for Ménière's disease, showed an increase of the SP voltage, whereas the AP voltage decreased. In benign positional vertigo, the SP voltage decreased, and the AP voltage increased, once during Trendelenburg positioning and again at the end of the test when starting position was resumed. During raised intracranial pressure after the Queckenstedt maneuver, round-window fistulas showed an increase of the SP voltage, whereas the AP voltage decreased considerably. At our clinic, stress electrocochleography has become an important neurootological test in the differential diagnosis of Ménière's disease.

Action Potentials↗
PubMed1999

The cervicogenic otoocular syndrome: a suspected forerunner of Ménière's disease.

Over a period of 4 years, 420 patients were observed with fullness in the ear, episodic vertigo, fluctuating hearing, and tinnitus. Of them, 182 patients showed normal hearing levels, a mild eustachian tube dysfunction, normal SP/AP ratios, mydriasis on the side of the affected ear, and a functional disorder of the upper cervical spine. These patients responded to conservative management, particularly physiotherapy. Additionally, 51 patients showed normal hearing levels, a mild eustachian tube dysfunction, an elevated SP/AP ratio suggesting endolymphatic hydrops, mydriasis on the side of the affected ear, and a functional disorder of the upper cervical spine. These patients were given a diagnosis of cervicogenic otoocular (COO) syndrome. Within this group, 43 patients did not respond to preceding conservative management, and 3 patients developed Ménière's disease within 12 months. Also within this group, 8 patients responded to physiotherapy only, with return of the SP/AP ratio to normal levels. A total of 187 patients had a sensorineural hearing loss, an elevated SP/AP ratio, mydriasis on the side of the affected ear, a functional disorder of the upper cervical spine; 186 had a mild eustachian tube dysfunction and had diagnosed Ménière's disease. Patients with a COO syndrome invariably responded to the insertion of a middle-ear ventilation tube, with return of the SP/AP ratio to normal levels and relief of symptoms. Patients with Ménière's disease had a mixed response. The COO syndrome is suspected to be a forerunner of Ménière's disease.

Adult↗