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P Amouch

Publications and source records attributed to P Amouch.

2 recordsLinked to original sources

[Groupamatic in the general organization of collecting and utilization of blood at C.N.T.S].

The automatization of immunohematological tests on Groupamatic equipments and its integration in a data management system of blood units and donor files has been brought about progressively, takinginto account the initiator status of the C.N.T.S. and its priviliged relationship with the manufacturer. A set of different problems was thus successively studied, the solutions of which lead to the development of new techniques, concerning the machine itself and its surroundings: --blood collection: -taking of blood sample on vacutainers containing anti-coagulant, without dilution, at a constant level and clot free; --identification: -connection between blood sample and blood unit by the creation of an identification number on twin labels (2 part card); -donor blood donation connection; --utilization of Groupamatic results: -edition of result listings; -study and use of an automated labelling of blood units; --setting up and daily updating of donor files: -blood collection data management; -creation of a badge--link between blood donation, files and donors. These constant improvements of both system and techniques have helped to put us within reach of the goal set as early as 1963 with Dr. C. Matte, that is to say the establishment of a fully automated system avoiding any intervention other than blood collection. Thus, due to the suppression of retranscription, this system increases the safety and enables the use of previously known donor characteristics.

Autoanalysis

HBs antigen in human plasma fractions.

Therapeutic fractions were obtained by fractionating human plasma containing HBs antigen, by the Cohn ethanol technique modified by Nitschmann. Plasmas with various HBs antigen titers were selected. The antigen was sought in each fraction by the techniques of counterelectrophoresis and radioimmunological detection in liquid phase. With the exception of very pure albumins, all fractions were found to contain the HBs antigen, though in variable proportions. A technique for the purification of albumin, applicable on an industrial scale, is proposed. It makes it possible to obtain an albumin fraction in which the HBs antigen cannot be detected by the most sensitive techniques, even starting with a plasma which is very rich in HBs antigen (titer 1/64 by counterelectrophoresis).

Blood Coagulation Factors