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Biomedical subjects

P Angelini

Publications and source records attributed to P Angelini.

At least 19 recordsLinked to original sources
PubMed2000

Fast procedures for coincidence-summing correction in gamma-ray spectrometry

Simplified and fast procedures for coincidence-summing correction in gamma-ray spectrometry were investigated. These procedures are based on the usual theoretical expressions of the correction factors, but differ in the determination of the total efficiency curve based on the following approximations: (a) replacement, below the knee efficiency value, of the total efficiency by the full-energy peak efficiency; and (b) use of linear interpolations (in log-log plot) between only two experimental points above the knee efficiency value; or (c) assumption of a peak-to-total efficiency ratio independent on the counting geometry; or (d) assumption of a constant relation between the peak-to-total efficiency ratios and the photoelectric-to-total cross section ratios. The above approximations were separately assumed for determination of the coincidence-summing correction factors for nuclides with complex decay scheme (133Ba, 134Cs, 152Eu) and for 60Co and 88Y measured on a 15% relative efficiency p-type coaxial HPGe detector, for three source-detector geometries: point source placed on top of and at 10 cm from the detector window, and 1 l Marinelli beaker filled with aqueous solution. The results were compared with those based on more accurate experimental determinations of the total efficiency curve from measurements of standard sources of eight different single-gamma-ray emitters. The usefulness of each simplified procedure is evaluated with respect to its accuracy and to the reduction of the number of standard sources and measurement time.

Journal Article↗
PubMed1998

Thrombolytics and left-sided prosthetic valve thrombosis. A case report.

Prosthetic valve thrombosis is a well-known condition. Because surgical treatment of prosthetic valve thrombosis is associated with a high mortality rate, the use of thrombolysis as therapy for this condition has gained popularity in recent years. In this article, we discuss the cases of 3 patients who presented to our institution with left-sided prosthetic valve thrombosis between 1994 and 1997. All 3 patients presented with New York Heart Association functional class III or IV symptoms, and all were successfully treated with urokinase. The use of thrombolytic therapy for left-sided prosthetic valve thrombosis is associated with low mortality rates, and therefore is an attractive alternative to valve replacement or thrombectomy. However, the risk of embolic and hemorrhagic complications precludes the use of thrombolysis in patients with large thrombi and in those with New York Heart Association functional class I and II symptoms; for these patients, the risk associated with thrombolysis exceeds surgical mortality rates.

Aged↗
PubMed1998

[The use of HIV-1 protease inhibitors. Their effects on AIDS-correlated outpatient and hospitalization activities. A catchment area study].

OBJECTIVE: To evaluate the effects of the use of protease inhibitors (IP) on the out-patient department's activities and hospitalizations of HIV-1 infected subjects. METHODS: From the December 1996 IP was available in our hospital, so the years 1996 and 1997 were studied. RESULTS: In the year 1997, 336 patients were visited with an increase of the 41% compared with the year 1996. In the 1997 the 45.2% of hospitalizations were related to AIDS, while in the year 1996 the 65.4% of them were related to AIDS. CONCLUSIONS: The use of IP had increased the activities of the out-patient department and certainly had a role in reducing the hospitalizations related to AIDS.

AIDS-Related Opportunistic Infections↗
PubMed1997

Neurocardiogenic syncope and Prinzmetal's angina associated with bronchogenic carcinoma.

A clinical case is presented illustrating a previously unreported association of (1) neurocardiogenic syncope of new onset in a 57-year-old man, (2) Prinzmetal's angina, and (3) bronchogenic carcinoma of the lung. Initiation of aggressive chemotherapy resulted in immediate suppression of both cardiac manifestations. This newly described paraneoplastic syndrome is discussed.

Aged↗
PubMed1997

[Classification problems in iatrogenic hepatic traumas. 10 years of personal experience: 17 cases].

The authors propose modifying Moore's classification of hepatic trauma in an attempt to classify and emphasise iatrogenic hepatic lesions. Although fortunately rare, iatrogenic hepatic trauma are particularly severe since they occur in patients with liver pathologies or precarious general conditions and are therefore characterised by a high mortality rate: 29% in a series of 17 cases.

Adolescent↗
PubMed1997

[Evaluation of the efficacy of image-guided drainage in the treatment of abdominal fluid collections].

In this paper the Authors report their experience in the diagnosis and management of abdominal fluid collections either primary or secondary to surgery. Sixty-eight patients with abdominal fluid collections were considered: in 28 cases an imaging guided percutaneous drainage was performed, while in 40 cases patients were treated with medical or surgical therapy. The Authors describe the different techniques, the approaches and the types of catheter used on the basis of the localization of the collections. The results show the efficacy of drainage procedures in 89% of the patients treated, without any major complication. Some considerations comparing patients treated with percutaneous drainage and patients who underwent different therapy as well as a review of the international literature are also reported. In conclusion the Authors affirm that percutaneous imaging guided drainage is the treatment of choice for abdominal fluid collections anatomically accessible, for the high effectiveness, good tolerability, low cost and minimal incidence of major complications.

Abdomen↗
PubMed1996

Stent placement in a patient with Takayasu's arteritis.

A 49-year-old woman with a history of Takayasu's arteritis underwent stent placement of the celiac and mesenteric arteries after unsuccessful balloon angioplasty. Stents may prove to be a beneficial alternative to angioplasty for treatment of the dense fibrotic lesions often associated with this disease.

Angioplasty, Balloon, Coronary↗
PubMed1996

High-risk coronary angioplasty assisted by active hemoperfusion. A feasibility study.

We assessed the effectiveness of distal hemoperfusion support during gradual, prolonged balloon inflation during percutaneous transluminal coronary angioplasty in high-risk patients. The patients were identified as having a poor left ventricular ejection fraction ( < 35%), > 50% of viable myocardium at risk percutaneous coronary balloon angioplasty, or both. A total of 64 procedures were performed in 61 patients. Angiographic success was achieved in 83 of 86 (96.5%) lesions treated with hemoperfusion support. Hospital complications included 1 patient who had a non-Q-wave infarction, 1 who had to undergo redo percutaneous coronary balloon angioplasty, and 5 who required coronary artery bypass operations. The hospital mortality was 7.8% (5 patients). This preliminary study indicates that hemoperfusion support can enable expeditious, simple, economical, and effective percutaneous transluminal coronary balloon angioplasty in a subset of labile patients in whom procedural failure frequently leads to sudden death.

Angioplasty, Balloon, Coronary↗