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P Assouline

Publications and source records attributed to P Assouline.

3 recordsLinked to original sources
PubMed2006

[Splenic metastasis from a bronchial carcinoma].

INTRODUCTION: Isolated splenic metastases from a bronchial carcinoma, without other visceral metastatic involvement, are exceptionally uncommon. CASE REPORT: The authors report the finding of an isolated splenic metastasis 21 months after a left pneumonectomy for an undifferentiated large cell carcinoma, initially staged pT3N1M0. The splenic metastasis presented as a major deterioration in general health and sharp pains in the left hypochondrium. Splenectomy confirmed the metastatic nature of the splenic tumour and relieved the severe abdominal pains. Two years after the splenectomy and with out adjuvant treatment the patient remains in complete remission. CONCLUSION: Splenectomy for a metastasis from a bronchial carcinoma should avoid the later complications of this type of metastasis: severe abdominal pain, splenic rupture and compression of neighbouring vessels. If the bronchial carcinoma is controlled locally and the splenic metastasis is isolated, splenectomy offers, perhaps, a further chance of prolonged survival.

Aged↗
PubMed2004

[Choroidal metastases in lung cancer].

INTRODUCTION: Ocular metastases are rare and their diagnosis can be difficult, being dependent on a combination of clinical examination of the eye, ultrasound, angiography and magnetic resonance imaging. CLINICAL CASE: We describe two cases of cases of choroidal metastases in patients with a bronchogenic carcinoma. In both cases the metastases presented at a late stage in the disease and occurred in association with cerebral metastases. One patient had an epidermoid tumour the other a small cell carcinoma. Loss of visual acuity, which was slowly progressive in the first case and abrupt in the second, led to the diagnosis of choroidal metastases. Following radiotherapy in a dose of 30 Gray delivered to the posterior segment of the eye, both patients' visual acuity recovered to near normal within a few weeks. CONCLUSION: If patients with lung cancer develop visual disturbance the possibility of choroidal metastases should be considered. Ocular radiotherapy can often ameliorate disabling visual disturbance, significantly improving quality of life.

Adult↗