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Biomedical subjects

P B Marcus

Publications and source records attributed to P B Marcus.

8 recordsLinked to original sources
PubMed1979

Convoluted secretory material in thyroid follicular epithelial tumors.

Electron microscopy may occasionally be useful, when routine histopathologic methods fail, in the typing of tumors, including those that present as metastases from occult primary sites. We describe a case in which the presence of an uncommon ultrastructural feature aided in establishing the thyroid gland as the source of a skeletal metastatic tumor.

Adenocarcinoma↗
PubMed1979

Glycocalyceal bodies and microvillous core rootlets: their value in tumor typing.

An ultrastructural study of the cell surface of lumen-forming tumors was carried out to determine the distribution of two morphologic markers seen in relation to the microvilli. These are membrane-bound glycocalyceal bodies and microvillous filament cores that penetrate the underlying cytoplasm as rootlets. They were found (especially when in combination) to be valuable in identifying tumors of what is referred to as intestinal-type epithelium, and could be seen in cases in which brush borders were absent. They have been demonstrated in intestinal-type carcinomas of the stomach and gallbladder, in adenocarcinomas of the small and large intestines and pancreatic ducts, in mucin-forming bronchiolar carcinomas, and in certain mucinous ovarian and endocervical tumors. Other tumors, whether mucin-producing or not, have been found to consistently lack these structures.

Adenocarcinoma↗
PubMed1978

Ectopic renal cell carcinoma: pathologists problem.

Renal cell carcinoma (hypernephroma) rarely develops as a primary tumor outside the normal confines of the kidney. Although many reports of so-called extrarenal hypernephroma may be found in the literature, very few cases appear to fulfill modern criteria for tumors of true renal origin. Strict criteria for the diagnosis of true extrarenal hypernephroma are proposed, and a case that partially conforms to these standards is presented.

Adenocarcinoma↗
PubMed1976

Meconium granulomas of the tunica vaginalis.

Meconium peritonitis results from perforation of the gastrointestinal tract during fetal life. Involvement of the tunica vaginalis may be the sole presenting clinical manifestation of the disease in the unusual event of the gut perforation resolving spontaneously. In such instances radiologically detectable calcification in the abdomen and scrotum is an essential diagnostic point. A case is described in which a baby had hydroceles and bilateral intrascrotal nodules but in which calcification was radiologically undetectable, presumably owing to its having undergon resolution. The typical histology of the nodules provided the diagnosis in this otherwise clinically undiagnostic case.

Calcinosis↗