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Biomedical subjects

P Bánovcin

Publications and source records attributed to P Bánovcin.

At least 19 recordsLinked to original sources
PubMed2005

Hemolytic uremic syndrome caused by verotoxin-producing Escherichia coli O26. Case report.

Verotoxin-producing Escherichia coli (VTEC) are nowadays among the most important emerging group of food-borne pathogens (VTEC strains cause gastroenteritis that can be complicated by the hemorrhagic colitis or hemolytic uremic syndrome, HUS). Escherichia coli 026 producing verotoxin 2 was isolated and its identity confirmed by examination of phenotype and genotype; the strain was first described in Slovakia in association with the development of HUS in a 4-year-old girl.

Child, Preschool↗
PubMed1992

[Carbocysteine in the treatment of recurrent bronchitis in infants].

In a group of 51 children aged 6-24 months the therapeutic effectiveness of the mucolytic preparation carbocysteine was tested and compared with the effect of Ipeca syrup. The effect was evaluated by means of a point score comprising changes of the clinical picture of the disease and the use of other laboratory examinations. The results of the examination revealed the more favourable effect of carbocysteine, as compared with a mixture of Ipeca syrup in the treatment of acute relapsing bronchitis in infants.

Bronchitis↗
PubMed1992

[Broncho-Vax and IRS 19 in the treatment of recurrent respiratory tract inflammation in children].

A group of 80 children with relapsing infections of the respiratory pathways (a minimum of three during the previous period) were investigated during the first year of the investigation (1987-88) with regard to the number and duration of the disease, absence from school, antibiotic consumption and use of bronchodilatating agents. In the subsequent year 1988-1989 the children were divided into a group treated with Broncho-Vaxom, a group treated with IRS 19 and a control group. Before the onset of administration and then every two months functional examinations of the lungs were made in the children. At the beginning of treatment and after its termination some immunological and laboratory values were examined. The effect of treatment was evaluated also subjectively by the parents and physician. Both preparations had a favourable effect on prevention of relapses of respiratory infections. This effects was more favourable after Broncho-Vaxom, in particular in prevention of inflammations of the lower respiratory pathways. IRS 19 eliminates relapses of infections of the upper respiratory pathways sooner.

Adjuvants, Immunologic↗
PubMed1991

Effect of prostaglandin F2 alpha on the contractile tissues of the respiratory system of the cat in experimental airway inflammation.

The in vitro reactivity of the smooth musculature of the trachea and lungs to PGF2 alpha, was studied in control cats and cats with experimental airway inflammation induced by turpentine oil. No changes were found in the reactivity of the tracheal smooth muscle, but the reactivity of the pulmonary tissue was significantly raised compared with the controls. The results indicate that PGF2 alpha may play a role in the pathogenesis of bronchial hyperreactivity after airway inflammation.

Animals↗
PubMed1990

[Treatment of secretory otitis media in children with carbocysteine (a group of 46 children)].

The authors evaluate 46 children with secretory otitis media. Half the patients were treated mostly conservatively; Mucodyn syrup 20 mg per day was administered per kg body weight. Treatment lasted 6-8 weeks. The other half of the patients was treated mainly by surgical methods. Oral administration of Mucodyn syrup is a suitable supplement of comprehensive treatment of children with secretory otitis media.

Carbocysteine↗
PubMed1990

[Fanconi's anemia].

Explore the source record for details and available documents.

Anemia, Aplastic↗
PubMed1989

Effects of atropine, acetylsalicylic acid, FPL 55712, and phentolamine on increased histamine responsiveness of cat lung strips under conditions of airway inflammation.

Our recent in vitro studies on airway smooth muscles of cats with turpentine oil inflammation showed an increase of isometric tension of the lung strips to histamine application. This communication describes the effect of atropine, acetylsalicylic acid, FPL 55712, and phentolamine on the histamine contractions of the lung strips derived from control and experimental groups of cats. Pretreatment of the lung strips with atropine and acetylsalicylic acid had no significant effect on histamine induced contraction. FPL 55712 significantly decreased the mean values of isometric contractions after the low doses of histamine in experimental groups of strips. The isometric contractions after higher doses of histamine were not affected by FPL 55712 in both groups of strips. The significant increase of histamine contractions of the lung strips induced by experimental inflammation was reduced by phentolamine. The role of alpha adrenergic receptors in the increased responsiveness of the inflamed lung tissues to histamine is discussed.

Animals↗
PubMed1988

Effect of histamine on the airway smooth muscle of cats under control and inflammatory conditions.

Previous in vitro studies on airway smooth muscles of cats with turpentine oil-induced inflammation of the airways have shown an increased sensitivity of the lung strips to histamine application. This effect was abolished by pretreatment with phentolamine. This communication describes the effect of prazosin and yohimbine on histamine responsiveness of strips of control and inflamed lungs. Prazosin had no effect on histamine-induced contraction of the control lung strips. However, the histamine-induced contraction of the experimental strips was depressed. Yohimbine depressed histamine-induced tension even in control lung strips. The role of alpha 1-adrenergic receptors in the increased responsiveness of the inflamed lung tissues to histamine is discussed.

Animals↗
PubMed1987

Influence of experimentally induced airway inflammation on the reactivity of cat lung parenchymal strips to histamine and acetylcholine.

The reactivity of cat lung parenchymal strips to histamine and acetylcholine in vitro was studied at various stages of inflammation of the airways induced experimentally by the intratracheal administration of turpentine oil or Staphylococcus aureus, both in aerosol form. With histamine, the contractile responses of the lung strips were enhanced depending on the stage of turpentine oil inflammation. Similarly, the lung strips responded more to histamine in the staphylococcal inflammation. The reactivity of the lung strips to acetylcholine remained mainly unaffected by either type of inflammation.

Acetylcholine↗
PubMed1987

Pharmacological analysis of reactivity changes in airways due to acute inflammation in cats.

Our recent in vitro studies on airways smooth muscles of the cat with turpentine oil inflammation showed the occurrence of a contractile response of tracheal preparations and a significant increase in the isometric tension of lung strips to histamine application. This study was aimed to establish whether histamine H2-receptors participated in the changed in vitro reactivity of the airways smooth muscles of cats suffering from experimentally induced airway inflammation. Pretreatment of control tracheal preparations, control and experimental groups of the lung strips by cimetidine did not change the character of the histamine response. Similarly, the amplitude of histamine relaxation, of the tracheal preparations partially contracted by carbachol was unchanged by experimental inflammation. Clemastine significantly shifted the histamine dose-response curves to the right in both groups of lung strips. However, significant differences in lung strip reactivity between control and experimental groups of cats were not eliminated. Our results do not support the role of histamine H2-receptors in the pathologically increased airway reactivity to histamine in vitro.

Airway Resistance↗
PubMed1987

Age- and body-weight-dependent changes in the reactivity to histamine of the airways smooth muscles in cats.

The relation between age and body weight and the reactivity to histamine of the tracheopulmonary contractile tissues was studied in cats in vitro. The reactivity of the tracheal smooth muscle to histamine decreased with increasing age from the newborn (100%) and one-month-old (57%) to the adult (0%) cat, whereas the amplitudes of contractions of lung strips increased. The amplitudes in adult animals also increased moderately with increasing body weight.

Aging↗
PubMed1985

Reactivity of cat tracheal smooth muscle to histamine under conditions of experimentally induced inflammation.

The reactivity of cat tracheal smooth muscle to histamine in vitro was studied at various degrees of inflammation of the airways induced experimentally by the intratracheal administration of turpentine oil or Staphylococcus aureus, both in aerosol form. Tracheal smooth muscle preparations from the control animals did not respond to histamine in doses of 10(-9)-10(-3) mol X 1(-1). In tracheal preparations from three groups of cats with turpentine oil inflammation induced 24 h, 48 h and 15 days previously, histamine caused contractions in 20, 70 and 24% of the cats, respectively, according to the degree of inflammation. All tracheal preparations from cats with staphylococcal inflammation responded to histamine by contraction. Atropine, acetylosalicylic acid and phentolamine did not abolish histamine contractions in tracheal preparations, but clemastine did.

Animals↗