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Biomedical subjects

P Baran

Publications and source records attributed to P Baran.

At least 19 recordsLinked to original sources
PubMed2000

Selective imidazolidine ring opening during complex formation of iron(III), copper(II), and zinc(II) with a multidentate ligand obtained from 2-pyridinecarboxaldehyde N-oxide and triethylenetetramine.

The condensation of 2-pyridinecarboxaldehyde N-oxide and triethylenetetramine yields a product with two imidazolidine rings, as proven by a solid-state X-ray structure analysis as well as by NMR solution spectra. This ligand, L1, undergoes a ring-opening reaction on complex formation with Cu(II), yielding [CuL2]2+ where L2 functions as a pentadentate ligand, containing only one imidazolidine ring. On complexation with Zn(II) and Fe(III), both rings are opened and the complexes [ZnL3]2+ and [FeL3]3+ with a hexadentate L3 ligand are formed. The recrystallization of [ZnL3]2+ from DMSO solution results in the complex [ZnL1(DMSO)2]2+ in which L1 behaves as a tetradentate ligand. Thus L1, L2, and L3 are structural isomers with two, one, or no imidazolidine rings, as confirmed by X-ray structure analyses. The intramolecular ring formation is the result of the nucleophilic addition of the N(amino) group to the electrophilic sp2-hybridized -HC delta+=N site. Owing to the absence of the chelate effect on the sp3-hybridized carbon atom belonging to the imidazolidine ring, the ring opening is facilitated and readily observed upon complex formation with Cu(II), Zn(II), and Fe(III).

Journal Article↗
PubMed1989

[The occupation of the pregnant woman in relation to the course and outcome of pregnancy].

Some occupations are associated with an extra risk during pregnancy. Intensive action is not involved (the relative risk does not exceed the value of 2,000) but with regard to the number of women in these categories it is a significant extensive factor. Based on the results of an analysis of a group of all naturally terminated pregnancies in the district of Gottwaldov in 1981-1983 (6166 pregnancies), as compared with the mean an increased ratio of reproductive losses was recorded in charwomen, hairdressers, teachers, engineers with university education. Prematurity was recorded in particular in waitresses, shop-assistants, nurses, other health workers and women doctors. Workers on the whole have relatively favourable results, however, the risk in these occupation more frequently develops into actual failure of pregnancy (haemorrhage in the 1st trimester, imminent premature child birth). These workers are also more protected by legal leave after a previous childbirth, as compared with other occupations.

Czechoslovakia↗
PubMed1989

[Adverse effects of the work process in relation to pregnancy].

Some characteristics of the working activity of pregnant women were investigated during statistical analysis of data pertaining to 6166 naturally terminated pregnancies in the Gottwaldov district (1981-1983). The threatening element from the aspect of spontaneous abortions in the first trimester is work done during most of the shift in a standing position without movement. There also the highest incidence of small-for-age and hypotrophic foetuses was found. Work involving constant movement is a risk and may lead to premature delivery. Manipulation with loads threatens pregnancy by reproductive losses (in particular a higher incidence of haemorrhage during the first trimester) and by prematurity. Social tension at the place of work also threatens pregnancy - at conflict in work places a significantly increased risk was proved. It was also proved that it is important to respect medical recommendation to transfer pregnant women to other work. As to associated factors, commuting was investigated and its adverse effect is particularly apparent when the distance is more than 25 km.

Adult↗
PubMed1980

[Position of patient-relevance to isotope nephrography in second half of pregnancy (author's transl)].

Diagnostic isotope nephrography of 63 women in the second half of pregnancy is reported in this paper. Positioning was changed for control checks, and major deviations were found to occur to the ING curve with patients in lateral position. There was, above all, an improvement in the excretion phase on the relieved side. Less variation was recorded from the secretion phase. Those findings should be taken into due consideration, particularly for diagnosis of ureter obstructions in advanced pregnancy. Lateral positioning is recommended for the above reasons also in cases of late gestosis, gestational cystopyelitis, and suspicion of intra-uterine retardation of foetal growth. Lateral positioning proved to be superior to genupectoral positioning. -- The above findings appear to provide additional evidence in support of a hypothetic proposition according to which mechanical factors are of sizeable importance to the genesis of urinary retention in advanced pregnancy. Therefore, no publication should be made without data on patient positioning.

Adult↗
PubMed1977

[Our experiences with Mayer-Ringpessary in the prevention of premature labor (author's transl)].

After very good results with a new model of the Mayer-Ringpessary made of organic glass the authors used this "unbloody cerclage" as a method of choice with all patients in their district (180 000 inhabitants) with partus praematurus imminens. It is necessary controls to apply the method in stage of this complication in good-time. There were below 10% of immature children in 405 high risk patients and only 1,2% to 1500 g. They succeded to delay the delivery in more favourable time to shorten the hospitalisation and unability considerably. Perinatal mortality was also favourably influenced. The details are in tables.

Adult↗