Biomedical subjects
Publications and source records attributed to P Bastit.
Three cases of abdominal sympathoma, a tumor generally affecting young children, presented with clinical symptomatology differing from that observed in infants. Diagnosis is much more difficult and the prognosis constantly fatal.
In this study we have been able to pull out 23 case histories of husbands of sterile wives out of a total of 839 patients who consulted us for diminished fertility. These 23 have the characteristics of "normal" male male population and serve as a reference group to estimate normal values of different parameters. The steps taken in this way give figures that are very little different from those obtained by other methods but once a still larger group have been analysed it would be possible by this method to work out the incidence of the different pathological states that can be found in the general population. An analysis of the differences found in our groups shows that the most significant parameter is the percentage of spermatozoa that are moving in straight lines. This means that future efforts should be directed to this parameter when automation or standardization is considered. There are normally random fluctuations in the parameters of healthy subjects but pathological pressures in subjects with lowered fertility mean that some of them vary in parallel coordinated directions. Because of this, seven different profiles can be worked out for different syndromes: Where the head alone is affected: macrocephalic spermatozoa, broken spermatozoa. Where the intermediate portion alone is damaged: a very thin intermediate portion. Where the tail alone is affected: spermatozoa with a short or absent tail. Where several parts of the sperm are affected: hook-shaped spermatozoa, double-headed spermatozoa, and rolled-up spermatozoa.(ABSTRACT TRUNCATED AT 250 WORDS)
Breast cancer rarely occurs in males, and reliable epidemiological and aetiological studies are scarce. The condition is one hundred times less frequent than in females and usually develops around the age of 60, i.e. 8 years later on average than in women. Its incidence, however, is high in patients with Klinefelter syndrome. Clinical symptoms and paraclinical data are similar to those of female breast cancer. The overall prognosis is considered as being more severe, but the difference is reduced when the results are expressed as corrected survival rate. Treatment is predominantly surgical, radiation therapy being usually reserved to cases where surgery is contraindicated or used to complement surgery. Since breast cancer is hormone-dependent, patients with advanced stage of the disease may benefit from suppressive hormonal treatment.
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The antalgic effects of tiapride by IM route are evaluated in a randomized study on 30 patients with different kinds of neoplasia-related pain. Using an average dose of 300 mg/day, the effectiveness was considered as excellent or good in 60% and equivalent to the reference drug. This effect was obtained after 30 minutes and lasted about 4 hours. The results compared closely with the reference drug. Tolerance was good with the rare problem of somnolence.
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