Biomedical subjects
P Bentsen
Publications and source records attributed to P Bentsen.
[Sleep apnea syndrome patients can in many cases get relief through surgery].
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[Cerebral complications in chronic acetylsalicylic acid poisoning].
A 60-year-old woman who for many years had been taking salicylate-containing tablets for headaches, was admitted to hospital, in a somnolent state, because of increasing weakness, tiredness, memory and speech disorders, and tinnitus. Laboratory tests revealed a decompensated metabolic acidosis (pH 7.25), renal insufficiency (creatinine 2.3 mg/dl) and a decreased Quick value (63%). Whole-blood acetylsalicylic acid concentration was markedly elevated to 330 micrograms/ml. After treatment of the acidosis with bicarbonate and forced diuresis she at first regained consciousness, but clouding of consciousness again occurred eight hours later progressing to coma with unequal pupils and seizure potentials in the electroencephalogram. Status epilepticus without motor component was diagnosed, perhaps the result of a dysequilibrium of acid-base balance between blood and cerebrospinal fluid. The signs and symptoms were quickly reversed under treatment with clonazepam.
[Infarct ECG following a lightning accident].
A 17-year-old man was resuscitated after being struck by lightning. The ECG showed a development similar to anterior infarction. The patient died on the 12th day due to irreversible brain damage. Autopsy showed normal myocardium.
A clinical study on the prolonged antihypertensive effect of clonidine in a sustained-release capsule formulation.
Eight patients with essential hypertension each received a single oral dose of 1 capsule of a sustained-release formulation of 0.25 mg clonidine in the morning for 3 consecutive days. Pulse ratio and blood pressure were measured in the standing and supine positions at specific intervals. After the first day of treatment, a significant decrease in blood pressure lasting 24 hours was recorded for the standing position. In the supine position, there was a progressive decrease in blood pressure which also attained significance on the third day of treatment. There was a progressive and significant reduction in mean arterial pressure from the first to the third day.