PubMed HealthSearch

Biomedical subjects

P Berger-Gross

Publications and source records attributed to P Berger-Gross.

5 recordsLinked to original sources

Auditory laterality in depression: relation to circadian patterns and EEG sleep.

Unmedicated endogenous (ED) and nonendogenous depressed (ND) patients were tested in the morning and evening on a dichotic click detection task and a dichotic consonant-vowel (CV) discrimination task. The ED and ND groups showed a morning to evening shift in lateral asymmetry for detecting dichotic clicks, which was opposite in direction to that previously seen for normal subjects. In contrast, there was no morning to evening shift in asymmetry for dichotic CV discrimination. Lateral asymmetry for dichotic click detection was significantly correlated with EEG sleep characteristics (sleep latency, REM period latency, REM time) and ratings of diurnal variation on the Hamilton Depression Scale. A reversal of the normal lateral asymmetry in the morning was associated with lengthened sleep latencies and with clinical ratings of diurnal variation.

Adult

Dichotic listening in the morning and evening.

Normal subjects needed greater intensity to detect dichotic and monotic click stimuli in the evening compared to the morning. Also, the asymmetry for detecting dichotic clicks shifted from morning to evening. The morning pattern of left ear lead advantage was absent in the evening. In contrast, there was no morning versus evening change in either overall accuracy or right ear advantage for consonant-vowel discrimination.

Acoustic Stimulation

Lateralized auditory processing in depression: dichotic click detection.

The intensity needed to detect dichotic click stimuli was measured in 14 bipolar depressed patients, 19 unipolar depressed patients, and 15 normal controls. The results replicated, in unmedicated bipolar depressed patients, an earlier finding of reversed lateral asymmetry in medicated affective psychotic patients. Two new findings concern the relation of lateral asymmetry patterns to diagnostic subtypes of the Research Diagnostic Criteria and symptom ratings on the Schedule for Affective Disorders and Schizophrenia. First, patients with bipolar disorders (history of mania or hypomania) were more likely than patients with unipolar disorders to display reversed lateral asymmetry. Second, greater severity of depressive or endogenous symptoms was associated with less lateral asymmetry.

Adult