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P Berruecos

Publications and source records attributed to P Berruecos.

6 recordsLinked to original sources
PubMed1976

Laboratory and clinical evaluation of tobramycin, a new aminoglycoside antibiotic.

The in vitro susceptibility to tobramycin of 1,466 bacterial isolates, including several genera and strains of common pathogenic gram-negative bacilli and Staphylococcus aureus, was determined by conventional serial dilution methods. Tobramycin exhibited marked in vitro antibacterial activity; almost all of the isolates tested were inhibited by less than or equal to 2.5 mug of the drug/ml. The antibiotic was used in the treatment of several types of infection in 29 patients with normal renal function. Observations were made on the therapeutic and secondary effects of the drug and on possible toxicity to the eighth cranial nerve. Clinical therapeutic results were satisfactory, The hearing of one patient was impaired, but the relation of this effect to tobramycin therapy is uncertain. Serum levels of the antibiotic were measured in 10 patients to investigate whether the drug accumulated during repeated administration. Mean serum levels of tobramycin 1 hr after intramuscular injection of 1.0 mg/kg were between 2.5 and 3.0 mug/ml on days 1, 3, and 6 of therapy. No accumulation of the antibiotic was observed after repeated administration.

Animals↗
PubMedDate not supplied

Cochlear implants: an international perspective--Latin American countries and Spain.

A questionnaire to determine the status of cochlear implant programs was sent to 11 countries in Latin America and Spain. General data were collected based on the population of each country (1996), estimate of population with hearing disorders based on the 10 per cent figure of the World Health Organization. number of people with congenital or acquired sensorineural hearing loss, and candidates for implantation (children and adults). The survey reports the number of people from each country who have been implanted, the cost with respect to per capita annual income (PCAI), and how many people with respect to PCAI would cover the cost of a country's entire program. Also reported are the number who were implanted pre- or post-lingually and the estimate of future new candidates for implantation per year. In conclusion, the paper discusses the ethical and socio-economic issues for cochlear implantation in so-called third world developing countries.

Adolescent↗