P Bodendieck | PubMed Health

PubMed1982

[Impeded recirculation after removal of circulatory obstructions by the structural viscosity of the blood].

Poststenotically developing aggregates of erythrocytes aggravate the recirculation of the blood vessel after removal of the obstruction. This is shown in model experiments in which blood vessels are observed vital-microscopically for a longer time. Place and extension of the diminished postischaemic blood circulation are variable and depend on the different size, the deformability, the adhesivity and localisation of the aggregates or erythrocytes.

Animals↗

PubMed1975

Postischaemic circulation disturbances.

Restoration of blood supply after ischaemic conditions in extremities and testes is inhibited by reversible intravasal aggregation of erythrocytes. This process is promoted by the increased permeability of the capillaries associated with the formation of oedema and the entailing increase of the haematocrit. For overcoming the stasis the increased structural viscosity caused by the aggregation of erythrocytes requires an increase in pressure as a starter effect which is not achieved by the flow pressure at once everywhere. Intravenously administered particles of Indian ink mark the formation and dissolution of aggregates. Even areas with originally normal blood supply may be obstructed by the later formation of aggregates. Thrombi on the walls of arterial and venous vessels and other lesions of the intima do not sufficiently explain the disturbance of perfusion. Oedema and extravasating leucocytes are found in the microcirculation. The parenchyma to be supplied shows formation of necrosis.

Animals↗