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Biomedical subjects

P Boesen

Publications and source records attributed to P Boesen.

8 recordsLinked to original sources
PubMed1988

Cyclic neutropenia terminating in permanent agranulocytosis.

A patient with cyclic neutropenia was followed for 20 years. After 16 years she developed a permanent agranulocytosis, and lived for nearly four years without neutrophils in the peripheral blood. Neither prednisone, lithium nor leuco- and plasmapheresis had any effect on the neutrophil count.

Adolescent↗
PubMed1988

Severe persistent cerebellar dysfunction complicating cytosine arabinoside therapy.

A case of persistent cerebellar dysfunction following high-dose cytosine arabinoside (Ara-C) treatment of acute myelogenous leukemia is reported. The symptoms developed after a cumulative dose of 24 g/m2, and 6 months after the start of symptoms, the signs of cerebellar damage were unchanged. The symptoms aggravated during a subsequent low-dose therapy with Ara-C, 15 mg twice daily. This supports the presumption that this adverse effect is caused by the cumulative dose rather than by high plasma concentrations.

Adult↗
PubMed1987

Giant cell arteritis, temporal arteritis, and polymyalgia rheumatica in a Danish county. A prospective investigation, 1982-1985.

The annual incidence of giant cell arteritis (the term used in this study to encompass the syndromes of temporal arteritis and polymyalgia rheumatica, occurring either together or alone) was prospectively determined in a Danish county that had a population of approximately 200,000. In a single year, 46 new cases of giant cell arteritis were diagnosed, a number which corresponds to an incidence in the overall population of 21.5/10(5), and to an incidence of 76.6/10(5) for individuals age 50 years or older. These rates are higher than those previously reported in retrospective studies. The 3-year followup of all patients showed no onset of other diseases that would require a revision of the original diagnosis. There was no deviation from the age- and sex specific malignancy rate or the mortality rate in the overall population. Women had an incidence rate 4 to 5 times higher than that seen in men. Symptoms, for the most part, were the same as those found in other studies; however, vision loss was not observed during the followup period. Point prevalence at the start of the study was 37.8/10(5), which is below the rates previously reported. This is probably because of failure on the part of participating physicians to record all cases.

Aged↗
PubMed1976

Timing of permanent tooth emergence in two Greenland Eskimo populations.

Mean times of emergence of the permanent teeth (except the first and third molars and mandibular central incisors) were studied cross-sectionally in an unmixed East Greenland population in 1957 and in present West Greenland Eskimo children. In spite of differences in racial and environmental conditions, practically no difference was found between the two samples in the timing of dental development in general, taking into account the average difference in emergence times of the individual teeth. Both samples showed advanced dental development in comparison with two unmixed Caucasoid and two unmixed Mongoloid populations. The mutual similarity in timing of tooth emergence between the East and West Greenland Eskimo children considerably greater than the similarity between each of the Eskimo samples and any of the other four populations.

Adolescent↗