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Biomedical subjects

P Bogdanski

Publications and source records attributed to P Bogdanski.

9 recordsLinked to original sources

Genetic markers among three population groups of Hungary.

Three ethnic groups from Hungary, the general population of Hungary, the Matyo and the Gypsies, were examined with respect to the genetic markers PGP, GLO1, GPT, ACP1, ESD, PGD, ADA, AK1, PGM1 subtypes, C3, BF, HP, GC subtypes, PI, TF subtypes and AMY2. Significant variations were noted for the gene frequencies of GPT and PGD between the Hungarian and Matyo sample. The Gypsies deviate in the systems of GLO1, ACP1, ADA, C3, BF and HP from the Hungarians.

Adult↗

Red cell and serum protein polymorphisms in three population groups of South Korea.

Genetic markers ACP1, PGM1 with subtypes, ESD, GLO1, PGD, GPT, PGP, C3, TF and GC with subtypes, BF, HP, AMY, PLG and PI, were studied in three populations in South Korea, one being the population of the industrial capital Seoul, the second a rural group from Taejon and the third the population of Cheju Island. For the polymorphic systems studied in the present work, a general similarity was observed among the three populations, with the exception of GPT and ACP1 (Taejon vs. Seoul) and subtypes of GC (Taejon vs. Cheiu).

Blood Proteins↗

Population genetic studies in three Chinese minorities.

Three minority ethnic groups from China (Mongolians, Koreans, Zhuang) were examined with respect to the genetic markers GLO, GPT, ACP, ESD, 6-PGD, PGM1 subtypes, C3, and TF. Significant variations were noted for the gene frequencies of GLO, GPT, ESD, sub PGM1 between Zhuang and Mongolians; for GPT, ACP, ESD, sub PGM1 between Zhuang and Koreans; and for GLO between Mongolians and Koreans.

Adolescent↗

Ecogenetic studies in Atacameño Indians.

Aldehyde dehydrogenase deficiency, N-acetyltransferase variation and the polymorphisms of alpha 1-antitrypsin, serum cholinesterase, paraoxonase, and delta-aminolevulinic acid dehydratase were investigated in 180 Atacameño Indians from the North of Chile. The genetic predisposition of these individuals for possible atypical reactions against environmental agents and drugs, as well as general implications of these findings, are discussed.

Aldehyde Oxidoreductases↗

Aldehyde dehydrogenase isozyme deficiency and alcohol sensitivity in four different Chinese populations.

Four different populations of China were studied regarding aldehyde dehydrogenase isozyme variation and incidence of alcohol sensitivity. While Korean and Mongolian minorities in the north showed an isozyme I deficiency with a frequency of about 25 and 30%, 45-50% of Zhuang and Han were deficient, respectively. Adverse reactions after alcohol drinking were mainly reported by those subjects who showed the lack of aldehyde dehydrogenase isozyme I.

Aldehyde Dehydrogenase↗

Genetic studies in Atacameño Indians: serum protein and red cell-enzyme polymorphisms.

Phenotype and gene frequencies among Atacameño Indians are presented for nine serum protein polymorphisms (Hp, Gc with subtypes, Tf with subtypes, Amy, C3, Bf, PLG) and nine red-cell-enzyme polymorphisms (AcP, PGM1 with subtypes, AK, ADA, 6-PGD, GPT, EsD, GLO). Four systems--Tf, Amy, AK, ADA were found to be monomorphic. In the PGM1 subtypes an extremely high frequency of PGM1a3 could be observed. In two samples a new Gc mutant was identified and classified as Gc1A26. In the EsD system an unusual phenotype was detected in one sample.

Adult↗

Continuous quality improvement: at the grassroots.

As a philosophy and a belief system, continuous quality improvement (CQI) provides the basis for organizational commitment to strategic leadership, customer focus, an empowered workforce, and reliance on evidence to improve processes and outcomes. This paper describes the process engaged in by the hemodialysis unit at St. Joseph's Health Care, London to formalize our CQI processes. The paper emphasizes: the selection of outcome measures, the strategies to link outcomes to improvement opportunities, and the resulting improvement projects. The formal commitment to CQI has affected both patient care and staff morale in many positive ways.

Hemodialysis Units, Hospital↗