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Biomedical subjects

P Bonding

Publications and source records attributed to P Bonding.

At least 19 recordsLinked to original sources
PubMed1999

Does bismuth subgallate have haemostatic effects in tonsillectomy?

Previous studies have shown that bismuth subgallate added to gauze swabs in tonsillectomy reduces the time to achieve haemostasis and probably reduces the risk of postoperative haemorrhage. All these studies have used bismuth subgallate in combination with adrenaline. In this randomised clinical study we investigated the effect of bismuth subgallate alone. A total of 204 patients were randomised into two groups. One hundred and six patients had swabs with bismuth subgallate. In the control group (n = 98), plain swabs were used. Operating time time to achieve haemostasis, peroperative blood loss, and incidence of postoperative haemorrhages were recorded. There were no significant differences between the two groups. We conclude that the evidence for using bismuth subgallate as a haemostatic agent in tonsillectomy is weak. The effect observed in previous studies can probably be ascribed to the effect of adrenaline.

Administration, Topical↗
PubMed1998

[Is postoperative hemorrhage a risk in ambulatory tonsillectomy?].

Day-case surgery is being used increasingly to improve health care efficiency. In Denmark, tonsillectomy is performed on an in-patient basis because of safety concerns regarding primary haemorrhage. This study aims at investigating the likely safety of day-case tonsillectomy by defining the incidence and timing of primary haemorrhage and thereby to establish a safe time period for a possible same day discharge. Retrospectively recorded data on 2,888 tonsillectomies were reviewed. Serious primary posttonsillectomy haemorrhage arose in 34 patients (2.7 percent), of which 65 percent presented within eight hours and 95 percent within 23 hours postoperatively. In view of the fact that one quarter of the patients with a primary posttonsillectomy haemorrhage experience it more than 12 hours postoperatively, tonsillectomy cannot be recommended as a safe routine day-case procedure.

Ambulatory Surgical Procedures↗
PubMed1998

The non-specific effect of endolymphatic sac surgery in treatment of Meniere's disease: a prospective, randomized controlled study comparing "classic" endolymphatic sac surgery with the insertion of a ventilating tube in the tympanic membrane.

A prospective, randomized study was carried out comparing the effect of two surgical modalities in the treatment of patients with Meniere's disease: insertion of an endolymphatic sac shunt and insertion of a ventilating tube in the tympanic membrane. A total of 29 patients, 12 males and 17 females, age 27-71 years, were operated on in two ear, nose and throat (ENT) departments. Of these patients, 15 had an endolymphatic shunt inserted and 14 had a ventilating tube inserted in the tympanic membrane. Postoperative follow-up was carried out in the department in which the patients had not been operated. The severity of the disease was scored pre- and postoperatively, and the results evaluated under the guidelines of the Committee on Hearing and Equilibrium (1995) for the diagnosis and evaluation of therapy in Meniere's disease. The patients in both groups had a statistically significant reduction in dizzy spells, measured 6 and 12 months postoperatively, and there was no difference between the groups. The pathophysiological explanation for the reduction in dizzy spells in each of the treatment modalities is debatable and the effect is non-specific. The patients' hearing and tinnitus were statistically unaffected by the treatment in both groups, though 2 patients in the shunt group developed severe hearing loss (anacusis/70 dB).

Adult↗
PubMed1997

Extensive cholesteatoma: long-term results of three surgical techniques.

During the years 1979-81, three different surgical techniques were used in the treatment of 87 ears with extensive cholesteatoma. All procedures were performed in one stage by the same surgeon. Ten to 13 years after the operations about 70 per cent of ears operated on by the canal wall up technique had developed a new cholesteatoma, which in most cases was recurrent, or a deep retraction pocket. A modification of this technique with mastoid obliteration resulted in a similar failure rate. In contrast, ears operated on by the canal wall down technique (in most cases with mastoid obliteration) had acceptable stability with a long-term recurrence rate of about 15 per cent. Most patients in the canal wall down group had a dry ear without significant cavity problems. Hearing in these patients was as least as good as hearing in patients with a preserved canal wall. We conclude that a meticulous one-stage canal wall down technique in ears with extensive cholesteatoma results in a high percentage of unproblematic, stable ears with satisfactory function. In contrast, if the posterior canal wall is preserved, recurrent cholestealoma is the rule more than the exception.

Adolescent↗
PubMed1996

Facial palsy in acute otitis media.

During the 17-year period from 1977 to 1994 a total of 23 patients in Copenhagen County were admitted to hospital with facial palsy, developed during acute otitis media. This corresponds to an annual incidence of 2.3 per million inhabitants. In the pre-antibiotic era it was estimated that 0.5% of patients with acute otitis media developed facial palsy. Our figures indicate a decrease of this complication by a factor of 100, to 0.005%. Although fourteen of the patients were children, the risk of an acute otitis media being complicated by facial palsy seems to be highest in adults (who have a low incidence of acute otitis media). All the children were < or = 3 years of age and 2/3 of the adults > or = 50 years of age. Complete remission was seen in all patients, except one. The time interval to complete remission was correlated significantly with the degree of the facial palsy on admission, as it was longest in the most severe facial palsies.

Acute Disease↗
PubMed1996

First branchial cleft anomaly.

A first branchial cleft anomaly is an unusual clinical condition and the clinical picture is similar to that seen in other much more common diseases. This combination may result in a diagnostic delay and insufficient and dangerous primary surgery, resulting in facial nerve damage. This paper reviews the embryological background of first branchial cleft anomalies, the varying clinical presentation and the surgical treatment, illustrated by three case histories. A revision of the most common classification system is proposed.

Adult↗
PubMed1995

Can ear irrigation cause rupture of the normal tympanic membrane?: an experimental study in man.

Rupture of the tympanic membrane (TM) during ear irrigation is a rare but unhappy event. In this study the maximum overpressures obtained in the deep part of the external auditory meatus (EAM) during ear irrigation were measured postmortem in 20 cadavers. The highest pressures were obtained in normal- or wide-dimension EAMs when a metal syringe was used. With this device, the median maximum overpressure was 240 mmHg (range 200-300 mmHg). Experiments with simulation of an obturating wax plug did not increase the maximum overpressure. Compared with the lowest overpressures which can rupture TMs the pressures measured in this study were insufficient to rupture normal TMs but sufficient to rupture atrophic TMs with the lowest tensile strength. This finding may have medicolegal implications.

Aged↗
PubMed1995

Modified midfacial degloving. A practical approach to extensive bilateral benign tumours of the nasal cavity and paranasal sinuses.

Midfacial degloving is a well-known technique for entering the nasal and paranasal cavities, the rhinopharynx and the base of the skull. We report our experience with a modification of midfacial degloving, applied to two patients with extensive bilateral benign tumours in the nasal cavities and the paranasal sinuses. No rhinoplastic procedure is necessary in this modification, and the access to the upper part of the nasal cavity is improved.

Adult↗
PubMed1994

Epithelial migration in mastoid cavities.

The epithelial migration in 18 dry ears with a cavity after surgery was studied by the ink-dot method and compared with the epithelial migration in 15 normal ears. A qualitatively normal centrifugal migration pattern was observed in all cavity ears. Considerable variation in migration speed was observed within the same cavity ear, thus a comparison with the migration speed in normal ears was impossible. No definite relationship was apparent between migration speed and the self-cleansing ability of the ear, which primarily appeared to be a function of the macroscopic appearance of the cavity (i.e. the presence of pockets or ridges). We conclude that epithelial migration is as important in maintaining the self-cleansing function and non-infected state in cavity ears as it is in normal ears.

Adult↗
PubMed1994

Implantation of electromagnetic ossicular replacement device.

Semi-implantable hearing aids consisting of permanent middle ear implanted magnet, either partial ossicular replacement prostheses (PORP's) or total ossicular replacement prostheses (TORP's) driven by an electromagnet placed in the ear canal have been tested on six patients undergoing surgery for chronic otitis. The surgical and audiological problems are described. The audiological results were excellent in all six cases. A functional gain of 40-70 dB can be obtained for entire frequency range of the audiogram.

Aged↗
PubMed1993

[Surgical treatment of otosclerosis. Long-term results].

UNLABELLED: At Glostrup Hospital, Copenhagen, exceptionally few stapedectomies were performed during the period 1979-1985. The audiological results five to eleven years after the operation were investigated in 64 patients. About half of the patients were operated using large fenester technique, the other half using small fenester technique. All patients but two were operated by the same expert surgeon. The initial results showed good stability with an unchanged median hearing gain of 30 dB. Eighty-five percent of the patients had an SRT < or = 35 dB HL in contrast to 89% at the 1-year follow-up (and five percent preoperatively). Eighty-two percent had an air-bone gap < or = 20 dB in contrast to 93% at 1-year follow-up (and 10% preoperatively). None of the patients had spontaneously developed severe sensorineural hearing loss, which was, however present in two patients as a direct result of the operation. In one of the patients it was caused by granuloma formation around the prosthesis, in the other patient it developed after a revision procedure. Both patients were operated using large fenester technique, which in general gave less satisfactory primary hearing improvement and less stable thresholds than small fenester technique. IN CONCLUSION: Even under conditions with few operations per year the overall long term results of stapedectomy are satisfactory when performed by few trained ear surgeons, and in particular if small fenester technique is used. The risk of sensorineural hearing loss is primarily related to the operation.

Adult↗
PubMed1993

Experimental pressure induced rupture of the tympanic membrane in man.

The size of the overpressure in the ear canal which causes rupture of the tympanic membrane (TM) in man (rupture pressure, RP) was determined in 90 subjects 7-112 h post mortem in connection with the autopsy. The equipment allowed an overpressure in the ear canal to be applied either gradually or suddenly. In 144 normal TMs it was demonstrated that the tensile strength of the TM increases post mortem. Corrected to the time 0 post mortem, RP of normal TMs ranged 0.5-2.1 kp/cm2, median 1.2 kp/cm2. It was found to be correlated to the age of the patient, i.e. RP decreased with increasing age. No correlation was found between RP and the application speed of the overpressure. Ninety-nine percent of the ruptures were localized to the pars tensa (63% to the anterior part of this structure) and typically had the shape of a minor tear. The RP of 23 TMs with atrophic scars was significantly lower, 0.3-0.8 kp/cm2, and the rupture typically had the shape of a larger defect. The results of this study indicate large intersubject variability of the tensile strength of the human TM. Some individuals are at increased risk of TM rupture at minor overpressures in the ear canal (e.g. during certain watersports, such as diving) which may carry medicolegal implications.

Adolescent↗
PubMed1992

The bone-anchored hearing aid. Osseointegration and audiological effect.

The results of treatment of the first 12 Danish patients with the Brånemark titanium implant system and the bone-anchored hearing aid (BAHA) are reported. All implants were osseointegrated, judged by 99mTC-scintigraphy, X-ray examination and clinical examination. Skin reactions were few, transient and short lasting. The patients experienced the BAHA to be superior to both conventional BC hearing aids and AC hearing aids in practically all respects. Speech discrimination scores in quiet and in noise were similar for the 3 types of hearing aids.

Adult↗
PubMed1992

Permanent, skin penetrating, bone-anchored titanium implants. A clinical study of host-reaction in bone and soft tissue.

In 12 patients with a skin penetrating retroauricular titanium-implant (Brånemark) the reaction in bone and soft tissue was studied. Observation time was 6 to 36 months. All implants were "osseointegrated", as assessed by repeated manual test, X-ray examination and 99mTC-scintigraphy. Soft tissue reactions appeared to be slight and clinically insignificant. However, all patients produced crusts around the abutment. When the abutment was removed varying degrees of inflammatory reaction in the skin penetration could be observed in most patients. A theory for the development and cause of the soft tissue reactions is proposed and changes in the operative procedure and the design of the abutment to reduce the host reaction are suggested. It is stressed that the clinical significance of this host reaction is uncertain and above all has to be weighed against the important benefits this implant system offers to a severely handicapped group of patients.

Adult↗
PubMed1990

[Permanent, percutaneous osseointegrated titanium implants. A review and preliminary results].

The present knowledge of the requirements for obtaining a stable percutaneous bone-anchored implant is reviewed. A Swedish implantation system, developed by Brånemark et al, is presented. The implants are made of titanium and the special design and manufacturing in combination with atraumatic operation technique in two stages assure that the implants are osseointegrated without interposed fibrous tissue. Soft tissue problems around the skin penetration are few and in most cases reversible. In the first seven Danish patients, implanted with the Brånemark-system for fixation of bone anchored hearing aid, stable osseointegration was achieved in all cases, judged clinically, radiologically and by 99mTc-methylene-diphosphonate scintigraphy of the cranium. In two cases brief, reversible soft tissue problems were present. The system has been shown to be most useful in otological rehabilitation, for fixation of bone-anchored hearing aids, and for fixation of prostheses of the external ear, eye or mid-face. The Brånemark-system has also been used in orthopaedic surgery, so far, however, only as endoprostheses, in particular for reconstruction of metacarpophalangeal joints.

Aged↗
PubMed1990

[Bone-anchored hearing aids. Preliminary results].

The bone conduction hearing aid is employed for patients who cannot tolerate treatment with air conduction hearing aids and for whom operation cannot offer permanent improvement of hearing. Conventional bone conduction hearing aids are, however, uncomfortable to wear, amplification is frequently less effective and sounds are often distorted. A new type of bone conduction hearing aid, the bone-anchored hearing aid (BAHA) is presented. In this, sound is transferred directly to the cranium via a percutaneous titanium implant. The results of treatment of the first six Danish patients are presented after a therapeutic period of 8-24 months. The subjective effect of treatment was satisfactory in all of the patients. They all employed their BAHA all day and found that the effect was better than the effect of air conduction hearing aids and conventional bone conduction hearing aids on practically all points. Speech discrimination investigations in quiet and noisy surroundings confirmed the subjective assessment although the differences between BAHA and the two other types of hearing aids were not as great as the patients subjective impressions. The bone-anchored hearing aid, BAHA, should, in our opinion, become the bone conduction hearing aid of the future for patients who have a permanent need for this. It represents considerable progress in treatment of a group of patients for whom treatment has hitherto been difficult and unsatisfactory.

Aged↗