Biomedical subjects

P Bonesvoll

Publications and source records attributed to P Bonesvoll.

14 recordsLinked to original sources

PubMed1983

Retention of Cu and Zn in the oral cavity following rinsing with aqueous solutions of copper and zinc salts.

Retention of Cu and Zn in the mouth after rinses with known volumes of aqueous solutions of the metal salts was measured by atomic absorption. The mean amounts retained in 10 subjects were 0.02 mg Cu and 0.22 mg Zn. These values represent approximately 31% of the Cu and 15% of the Zn originally in the rinse. The intraindividual variation (s.d.), estimated by three mouthrinses at weekly intervals in three subjects averaged 2.1% for Cu and 2.3% for Zn. Following a rinse the salivary concentration of Cu and Zn decreased rapidly during the first 4 h, approaching prerinse levels.

Adult↗

PubMed1979

Determination of fluoride and chlorhexidine from chlorhexidine/fluoride-containing dentifrices.

The intention of the present experiment was to study the effects of a possible interaction between fluoride and chlorhexidine when both agents were incorporated in the same vehicle. The amount of fluoride extractable from dentrifrices containing 0.1% NaF and the fluoride ion activity were not reduced by the addition of 2% chlorhexidine digluconate. Less than 50% of the added chlorhexidine was available when the dentifrices were dissolved in deionized water. This was not affected by the presence of fluoride. The in vitro antibacterial activity of the chlorhexidine-containing dentifrices was not reduced by the addition of fluoride. Approximately 40% of the chlorhexidine was retained in the human oral cavity after brushing for 1 min with both the chlorhexidine- and the chlorhexidine/fluoride-containing dentifrice. Thus the binding of chlorhexidine to vehicle ingredients when dissolved in water is probably too weak to affect the retention in the mouth.

Bacteria↗

PubMed1978