Detection of ICAM-1, ICAM-2, ICAM-3, PECAM-1 and VCAM-1, evaluation of hypercoagulable state and platelet aggregation in hemoglobinopathy patients with erythroblasts.
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Adolescent↗
Biomedical subjects
P Bonomo
Publications and source records attributed to P Bonomo.
Azoospermia in a patient with sickle cell disease treated with hydroxyurea.
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Adult↗
Evaluation of a new 5-log filter or packed red cells leucodepletion.
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Erythrocyte Count↗
Hepatitis C virus transmission.
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Adolescent↗
Double heterozygosity for haemoglobin Malmø and beta-thalassaemia traits, with unusually high haematocrit values, in a Sicilian man.
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Hematocrit↗
[The behavior of left ventricular hypertrophy after surgical correction of aortic and mitral insufficiency].
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Adult↗
[Effect of antihypertensive therapy with clonidine and alphamethyldopa on the indirect oxygen consumption index of the myocardium at rest and during exertion].
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Adult↗
[The significance of electrocardiographic changes of an ischemic type in athletes].
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Adult↗
[Mitral prolapse in young athletes].
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Adolescent↗
Double heterozygosity for hemoglobin Malmö [beta 97 (FG 4) His----Gln] and beta-thalassemia traits.
A 32-year-old Sicilian man had marked erythrocytosis (Hb = 23.0 g/dl, RBC = 10.5 x 10(12)/l, MCV = 71 fl, Hct = 84-92%, a 4.5 times increase in total erythropoies) and saphenous system varices, without other clinical abnormalities. By Hb electrophoresis, an abnormal Hb migrating slightly more anodally than Hb A was found. HbA0 was almost completely absent. The abnormal Hb was recognized to be Hb Malmö [beta 97 (FG4) His-Gln], a human Hb variant with greatly increased oxygen affinity. The patient was also a carrier of the beta-thalassemia trait. The father of the propositus was a heterozygous carrier of Hb Malmö (about 40% of total Hb), while his mother had only a beta-thalassemia condition. This is the first reported case of double heterozygosity for both Hb Malmö and beta-thalassemia, thus producing complete absence of normal Hb.
Adult↗