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Biomedical subjects

P Borrello

Publications and source records attributed to P Borrello.

11 recordsLinked to original sources

[The microbiological characterization of the bioaerosol and leachate from an urban solid refuse dump: preliminary data].

The present paper shows the results of an experimental study aimed at arranging a microbiological characterization of bioaerosol and leachate resulting from a sanitary landfill for solid urban waste situated near Rome. Bioaerosol sampling was performed by using the active sampling method referred to as surface air system, that is extensively used during indoor environmental monitoring. The microorganisms (bacteria and fungi) believed to be of relevance on bioaerosol and leachate with a view to hygienic risks, were investigated in order to estimate the potential risks to which the population and the workers can be exposed and consequently to allow corrective measures by monitoring campaigns of the examined matrices and by models of low environmental impact landfill.

Aerosols↗

Evaluation of undiluted N-butyl-2-cyanoacrylate in the endoscopic treatment of upper gastrointestinal tract varices.

BACKGROUND AND STUDY AIMS: Endoscopic obliteration of upper gastrointestinal tract varices using N-butyl-2-cyanoacrylate has been proposed by some authors. The aim of the present study was to evaluate prospectively the efficacy and safety of this technique, using the undiluted substance, in obtaining hemostasis of bleeding upper gastrointestinal tract varices, as well as definitive eradication of varices located in the gastric fundus and duodenum. PATIENTS AND METHODS: We carried out variceal injections of N-butyl-2-cyanoacrylate in 80 patients (51 males, 29 females, mean age 68 years, range 19-80) with upper gastrointestinal tract varices. In 24 patients, the varices were located in the esophagus, in 54 in the gastric fundus, and in the remaining two they were in the duodenum. Forty-eight patients were treated for active variceal bleeding, and the other 32 were treated electively. RESULTS: Hemostasis was achieved in 43 of the 48 patients (89.6%) treated for active variceal bleeding. Eradication was obtained in 49 of the 56 patients (87.5%) with gastric or duodenal varices. Overall complications occurred in 11 patients (10.4%). In two patients, embolization was found, and in a further two patients it was clinically suspected, but could not be proved. Ten patients (12.5%) died during the treatment period, six due to uncontrolled bleeding, two due to rebleeding, and two due to liver failure. CONCLUSIONS: Endoscopic injection of N-butyl-2-cyanoacrylate appears to be both safe and effective in the treatment of bleeding gastrointestinal tract varices. The relative value of the undiluted substance versus the diluted one should be further evaluated.

Adult↗

Effects of ozonized autohaemotherapy on human hair cycle.

The present paper deals with the effects of ozonized autohaemotherapy on the human hair cycle in subjects suffering from androgenetic alopecia. The microscopic observation of hairs (trichogram) of 42 subjects (age range = 17-40 years) was carried out before and after cycles of ozonized autohaemotherapy according to the European scientific protocol. The dosage of ozone was 2500-3000 micrograms for each treatment, one cycle consisting of 16 treatments. Results showed a marked improvement of the hair cycle.

Adolescent↗

[Chronic idiopathic intestinal pseudo-obstruction associated with volvulus of the transverse colon. The identical mode of clinical presentation and of the intestinal manometric pattern in monozygotic twins].

Two monozygotic female twins with chronic idiopathic intestinal pseudo-obstruction associated with transverse colon volvulus are described. Quite similar clinical events and temporal coincidences characterized the symptoms which has preceded and followed right colectomy undergone by both of them due to intestinal volvulus. The esophageal, gastroduodenal, colonic and anorectal manometric investigation revealed very similar alterations in both girls. Increased amplitude of distal contractions of the esophagus, a depressed fasting antro-duodenal motility, with absence into antrum and oro-aboral non-propagation in the duodenum of the phase III activity of the interdigestive motor complex were the main findings along with a state of pronounced colonic hypomotility and an hypoesthesia of the rectal ampulla to the volumetric stimulus. This report indicates the association between chronic intestinal pseudo-obstruction and transverse colon volvulus in monozygotic female twins, and it points out the rarity both of the specific symptomatic coincidences and the similar clinical events and of the almost absolute identity of the intestinal motor patterns.

Adult↗

Atrichia and papular lesions: report of a case.

We report a case of atrichia with papular lesions in a 4-year-old girl. The scalp was completely hairless since birth, except for dark, shiny, coarse hair on the frontoparietal region. Eyelashes and eyebrows were sparse. Numerous papular lesions developed on the hairless scalp, cheeks and neck during the second year of life. Teeth and sweating function were normal. The family history was negative. Histologic examination of a papular lesion showed the presence of a keratin-filled cyst in contact with the overlying epidermis. The pathology of the bald scalp showed the presence of tubular epithelial structures devoid of hair bulbs extending from the epidermis to the deep dermis and the superficial hypodermis. Sebaceous and outer root sheath differentiation was evident in most of the tubular structures that also frequently contained small ducts surrounded by two or three layers of flat epithelial cells. The superficial dermis contained horny cysts, similar to those present on the cheeks.

Alopecia↗

Loose anagen hair in a child with Noonan's syndrome.

We report on a 4 1/2-year-old girl affected by loose anagen hair and Noonan's syndrome. The girl had short, blond, easily pluckable hair that had never been cut. The trichogram showed an absolute prevalence of abnormally shaped anagen bulbs lacking inner and outer root sheaths. A scalp biopsy evidenced a marked cleft formation between fragmented inner root sheaths and irregularly shaped hair shafts.

Child, Preschool↗

Arsenic and heavy metals in leachate from a real landfill and a laboratory landfill.

A preliminary study, based particularly on Arsenic and some heavy metals determination (Cd, Cr, Hg and Pb) in three leachate tipologies produced from municipal waste landfill plant, lab-scale aerobic landfill, lab-scale anerobic landfill was undertaken. Leachate was collected and analysed monthly; samples were homogenized and then, all heavy metals were determined after mineralization, except for Hg, determined before mineralization, due to his high volatility. In all samples pH was measured. In general we can say that low concentrations of the elements analyzed were found in all kinds of landfills considered; in particular, in the lab-scale anaerobic reactors, where low pH values have been found, we have a more considerable mobilization of As and the others heavy metals, moreover due to the behaviour of these elements.

Aerobiosis↗