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Biomedical subjects

P Boruta

Publications and source records attributed to P Boruta.

16 recordsLinked to original sources
PubMed1992

[Abnormal CT brain scan during acute lymphoblastic leukemia in children].

The results of CT brain scans were evaluated in 96 children with acute lymphoblastic leukemia in different stages of the disease. Practically normal findings were recorded at establishing the diagnosis (17 children), with the exception of infiltration of the brain and meninges in one patient. Examinations performed after induction chemotherapy (31 children) revealed abnormal CT scans in 55% of the children concerning most frequently dilatation of the cerebrospinal fluid pathways and exhibiting less frequently hypodense foci in the white matter. At check-up examinations after 9 months (following prophylaxis of CNS leukemia) these deviations from the norm had disappeared in some patients, in others they persisted and in the rest of the patients they were found to be aggravated. Examinations carried out several years after treatment completion (40 patients) showed abnormal CR scans in 43% of the patients. These involved particularly derangements in the density of the white matter which were of leuko-dystrophic type and atrophic changes characterized by dilatation of the cerebrospinal fluid pathways. The recorded changes in the CT brain scans were more pronounced in patients with high-risk forms of leukemia and intensive prophylaxis of CNS leukemia.

Adolescent↗
PubMed1991

Disorders in neuropsychological development and their relation to computed tomography brain scan in children with acute lymphoblastic leukemia in long-term remission.

In a group of 71 children with acute lymphoblastic leukemia in long-term remission lasting 4 to 15 years different disorders in their neuropsychological development were found. The disturbances observed were as follows: Emotional disorders in 88%, personality development disorders in 65%, mental retardation in 58%, signs of CNS dysfunction in 54%, and neurological disorder in 31% of children. Abnormal computed tomography brain scans were present in 49% of patients. They consisted mainly of two types: Hypodense areas of the white matter were observed in 23% and widening of the ventricular system and subarachnoidal spaces was present in 26% of children. Statistical evaluation showed significant relations between CT brain scan abnormalities (mainly hypodense changes) and neurological disorders as well as the presence of signs of CNS dysfunction and disorders of personality development. Emotional and mental changes did not correlate with abnormalities of CT brain scan findings.

Adolescent↗
PubMed1990

[Intracerebral hemorrhage in hypertensives: diagnosis, therapy and prognosis].

The authors analyzed 98 cases of intracerebral haemorrhage in hypertonic subjects from the aspect of the clinical course, CT findings and therapeutic results. Thirty-seven patients were treated by surgery and 61 had medicamentous treatment. The acute mortality rate in operated patients was 57% in non-operated ones 30%. The patients with haemorrhage in the putamen formed the majority of the group and had a higher mortality rate than patients with other sites of haemorrhage. The state of consciousness on admission and the size of haematomas influenced in a significant way the acute mortality rate of patients. Fifty-nine patients were followed up for an average period of 34 months. Of those 19% died and 54% attained a fair restoration of the clinical condition. Only 5% returned to work.

Adult↗