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Biomedical subjects

P Bosso

Publications and source records attributed to P Bosso.

14 recordsLinked to original sources

Responsiveness to life-threatening obstetric emergencies in two hospitals in Abidjan, Côte d'Ivoire.

OBJECTIVES: To document the frequency of severe obstetric illness, and the intervals between admission or decision and life-saving surgery and the factors contributing to delays, which were reported during case reviews in two hospitals in Abidjan, Côte d'Ivoire. METHODS: The study was conducted in the teaching hospital in Cocody (CHUC) and the district hospital in Abobo (FSAS) in 2000-01. All severe obstetric cases were inventoried over a period of 1 year, and a subset of cases selected for in-depth review. For the 23 audited cases requiring emergency surgery, the interval between admission/decision and surgery was determined and reasons for the delays examined. FINDINGS: The yearly incidence of severe obstetric morbidity was 224.5 and 11.8 per 1000 live births in the CHUC and FSAS respectively. In CHUC, the decision-to-delivery time was extremely long (median 4.8 h) and this was largely determined by the time needed to obtain a complete surgical kit (median 2.8 h), either because the family had to pay for it in advance or because the kit lacked some essential components, which had to be bought separately. In FSAS, the decision-to-delivery time was much shorter (median 1.0 h). CONCLUSION: The interval between decision and emergency obstetric surgery substantially exceeded the 30 min generally advocated in industrialized countries. The reasons for the long delays were multiple and complex, but the main factors governing them were the huge case load of severe cases and the absence of any clear policy towards ensuring prompt and adequate treatment for life-threatening emergencies. In-depth reviews of cases of severe obstetric morbidity focusing in particular on the timing of emergency treatment could increase the responsiveness of the health system and providers to the needs of women requiring emergency obstetric care.

Cote d'Ivoire↗

[Breast lymphoma].

Primary malignant lymphomas of the breast are uncommon findings, representing 0.12% to 0.53% of all breast cancers. Secondary lymphomas are also uncommon, but they make the most frequent metastatic breast cancers. From January 1989 through December 1992, at the Department of Radiology of the University of Perugia, the authors observed 6 cases of breast lymphoma--1 primary and 5 secondary lesions--in women 52 to 67 years old (average 60 years). The only primary lymphoma was unilateral, multiple and localized on the right side; the secondary ones were diffuse and bilateral in 4 cases and unilateral and nodular in 1 case. The clinical findings were always suggestive of a malignant lesion and so were the mammographic and US findings in 4 diffuse lesions--3 bilateral and 1 unilateral cancers; in both the primary lymphoma and the secondary nodular lymphoma mammography showed benign patterns. Diagnosis was made in all cases following biopsy or resection of the breast mass; all the lymphomas were of the non-Hodgkin's type. The authors report on the major clinical, mammographic and US features of this unusual disease and include a short review of the relative literature.

Aged↗

[Mammography and echography in the study of breast prosthesis].

Between October 1990 and December 1991, the authors studied 58 women with breast implants (46 monolateral and 12 bilateral prostheses) by means of clinical examination, mammography, and US. The patients' age ranged 31-56 years (mean: 32). Thirty women had undergone subpectoral implantation, 22 subcutaneous and 18 retroglandular. In the group of subpectoral prostheses, 4 women had periprosthetic fibrosis and 3 presented benign calcifications; in 1 case both fibrosis and calcifications were observed. In the depiction of retroglandular implants, US appeared to be very useful: indeed, it detected 3 fibroadenomas and 5 cysts that had been missed at mammography. The only 2 breast carcinoma recurrences (1 non-palpable lesion, confirmed at surgery) were observed in patients with retrocutaneous prostheses. Both mammography and US currently play a major role in the follow-up of women with breast implants. Benign complications and breast cancers can be promptly detected even in patients with no palpable findings.

Adult↗

[Benign monoclonal gammopathies. Case reports].

30 cases of patients presenting a benign monoclonal gammopathy (b.m.g.) have been studied, stress being laid on concomitant conditions, cases with likely typical symptomatology, atypical variations over time in certain patients of the monoclonal Ig level, and cases which, before they can be called benign, need further controls. Two cases of transitory b.m.g., one in a child, with double polymerization state, are also presented.

Adult↗

[Benign monoclonal gammopathies. Critical review].

During a review of the relevant literature, the view is expressed that the term "monoclonal" expresses no more than an operative concept. A classification of the benign monoclonal gammopathies is proposed in accordance with their aetiopathogenesis. Stress is laid on the importance of antigen stimuli and self-maintenance of the tumour mass below a certain number of cells. Reference is made to the possible typical symptomatology and criteria for the differential diagnosis of myeloma and Waldenström's disease are put forward. Inter alia, emphasis is placed on the little significance of Bence-Jones proteinuria for the purpose of differentiation. Models of atypical behaviour are presented.

Diagnosis, Differential↗

[Mammography and echography in male breast pathology].

From January 1988 through December 1991, 81 men were examined for breast enlargement or mass in our Institute, by means of clinical examination, mammography, and US. The patients' age ranged 15-71 years (mean: 52 years). Of 81 studied patients, 71 had gynecomastia, 8 had adipomastia, 1 had an infiltrating ductal carcinoma, 1 an angiofibrolipoma and 1 a simple cyst. Both the carcinoma and the cyst were associated with gynecomastia. Three mammographic patterns of gynecomastia were observed: a glandular pattern in 42 cases (32 bilateral and 10 monolateral), a dendritic pattern in 12 (8 bilateral and 4 monolateral), and a nodular pattern in 15 (9 bilateral and 6 monolateral). On US, gynecomastia appeared diffuse in 54 patients and focal in 15. The infiltrating ductal carcinoma was clinically evident; no asymptomatic cancers were detected. Surgical biopsy was performed in 40 cases. A good correlation was observed between mammographic and US signs. The combined use of the two modalities can improve diagnostic accuracy. Biopsy must be performed in all questionable cases.

Adolescent↗