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Biomedical subjects

P Bottin

Publications and source records attributed to P Bottin.

9 recordsLinked to original sources
PubMed2005

[Primary orthostatic tremor].

Primary orthostatic tremor is a particular tremor exclusively present when a subject is standing. Patients experience a severe disabling sense of unsteadiness. Walking, sitting and lying down are unaffected Neurological examination and cerebral imagery are normal most of the time. Electromyography in standing position confirms the diagnosis in showing a regular rapid tremor with a frequency of 12 to 18 Hz. Its physiopathology is partially unknown. A few symptomatic therapies can be proposed.

Dizziness↗
PubMed2005

Prophylaxis of the epilepsies: should anti-epileptic drugs be used for preventing seizures after acute brain injury?

In many circumstances antiepileptic drugs are used in patients who have never presented any clinical epileptic seizures. These substances are administered on the assumption of a potential risk for the patients of developing acute or delayed chronic seizures after brain injuries such as trauma, stroke, hemorrages or even neurosurgical interventions. The aim of this paper is to propose therapeutic guidelines for the management of this prophylactic attitude in epilepsy based on basic research and clinical practice in the French community in Belgium. We will distinguish between the prevention of acute (early onset-provoked) seizures and a delayed truly post-lesional (unprovoked) epilepsy. Some therapeutic goals can be achieved under the former circumstances whereas in the latter situation we all agree for the absence of any coherent antiepileptic prophylactic behaviour.

Acute Disease↗
PubMed2003

Therapeutic issues in women with epilepsy.

Approximately 20% of people with epilepsy are of childbearing potential and about 3 to 5 births per thousand will be to women with epilepsy. Both epilepsy and antiepileptic drugs can cause specific problems in women and embryos (less than 8 weeks of gestational age) or foetuses (more than 8 weeks of gestational age). The aim of this paper is to discuss therapeutic issues for the management of women with epilepsy: initiation of antiepileptic therapy, contraception, pregnancy, breast feeding and menopause. Some fertility issues are also discussed.

Anticonvulsants↗
PubMed2003

[Statins for the brain?].

Whether cholesterol lowering decreases risk of stroke has long remained unclear. Large epidemiological studies have found only weak links between cholesterol levels and stroke. Recent studies with statins, more potent cholesterol lowering agents, have now demonstrated significant reductions of stroke incidence and total mortality when administered for secondary prevention in patients with wide ranges of cholesterol values. It remains unknown if a statin is superior to others for the secondary prevention of stroke.

Brain↗
PubMed1991

[Fissure caries: the correlation of clinical and radiological data].

The goal of this research was to evaluate the conventional means of clinical (mirror and probe examination) and radiological diagnosis (bitewing radiographs) of occlusal caries of first permanent molars during the post eruptive period. These teeth showed colored or non-colored fissures, and none of them had conservative or preventive obturations, or dentinal caries. Four experienced dentists independently evaluated the trials, diagnosed the lesions and advised a treatment. The effective lesions were shown by opening minimal preventive cavities, which were then obturated with amalgam. The results showed the lack of precision for the early diagnostic means of initial pit- and fissures-caries, and differences and errors of evaluation performed by the dental professional with respect to their diagnosis and proposed therapeutic choice. The effective lesions demonstrated the high incidence of pit- and fissure-caries in permanent molars during the post eruptive period.

Adolescent↗
PubMedDate not supplied

[Reversible posterior leukoencephalopathy syndrome].

Reversible posterior leukoencephalopathy refers to a clinicoradiological syndrome observed in patients presenting with acute or subacute symptoms of various intensity including seizures, headache, vomiting, confusion and visual abnormalities. The radiological features are reversible bilateral white matter abnormalities predominantly located in the posterior regions of the cerebral hemispheres, demonstrated by computed tomography or, better, by magnetic resonance imaging. This syndrome mostly occurs in patients with hypertensive encephalopathy or in immunosuppressed patients. The recognition of this syndrome is critical as delay in the diagnosis or treatment can result in permanent neurological deficit while early prompt control of blood pressure or withdrawal of causative drugs can reverse the syndrome.

Adult↗