[Encephalopathy in cat scratch disease].
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Animals↗
Biomedical subjects
P Boulan
Publications and source records attributed to P Boulan.
[Paraganglioma of the cauda equina. Clinical aspects and MRI. Apropos of a case].
The clinical and imaging features of a paraganglioma of the cauda equina are presented. A peridural anesthesia revealed the cauda equina compression syndrome in a 68 years old man who presented first with a urinary retention. Total surgical excision of a long round-shaped encapsulated tumor was uneventful. Macroscopically this lesion filled up the spinal canal and resembled to a meningioma. It was firmly attached to the filum terminale. Adjacent large arterialized vessels visible on MRI were spared. Although the diagnosis could be evoked pre-operatively on some suggestive patterns on the MRI, the pathological findings finally confirmed the diagnosis of paraganglioma. Along with the evidence of specific light microscopic features, the use of an immunocytochemical demonstration of synaptophysine in these tumors allows a confident diagnosis to be made.
Aged↗
Spontaneous and 5HT-induced cyclic contractions in superficial temporal arteries from chronic and episodic cluster headache patients.
Superficial temporal arteries (STAs) are abnormally dilated in the painful side during cluster headache (CH) attacks. We have assessed the possible dysfunction of these arteries by comparing in vitro the reactivity of STAs removed from the painful side of CH patients during a cluster of attacks with that of STAs from patients free of CH. The responses to KCl and norepinephrine (NE) of both types of arteries were similar. Serotonin (5HT) induced a classical dose-dependent constriction in arteries from non-CH patients, but systematically triggered rhythmic contractions in arteries from episodic CH patients. Arteries from chronic CH patients also showed spontaneous rhythmic contractions. In both cases, this activity was stopped by calcitonin gene-related peptide (CGRP) but, even in the presence of CGRP, it could be restored by low concentrations of 5HT. Thus, 5HT, unlike NA, can trigger rythmic activity in STAs of CH patients and may play a major role in CH through abnormal smooth muscle cell reactivity.
Adult↗