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Biomedical subjects

P Bourgon

Publications and source records attributed to P Bourgon.

4 recordsLinked to original sources
PubMed1985

Pupillary abnormalities induced by argon laser photocoagulation.

Twenty-two patients who underwent panretinal argon laser ablation for proliferative diabetic retinopathy were studied for post-laser pupillary abnormalities. All 22 patients developed sector palsies of the iris sphincter. Fifteen demonstrated supersensitivity to 0.125% pilocarpine in the treated eye. Four of 12 patients developed accommodative paresis in the treated eye. Six showed light near dissociation in the treated eye. The sector palsies and associated cholinergic supersensitivity of the iris sphincter, the accommodative paresis, and light near dissociation imply that the laser treatment damaged the ocular parasympathetic innervation.

Adult↗
PubMed1978

Cholinergic supersensitivity of the iris sphincter in Adie's tonic pupil.

In patients with unilateral Adie's syndrome, we compared the relative supersensitivity of the tonic pupil to methacholine hydrochloride (Mecholyl 2.5%) and pilocarpine 0.125%. We tested a large series of patients and photographed the pupils before and 30 minutes after the eyedrops. In a group of 36 patients, Mecholyl was positive in 64% of the tests; and in a group of 20 patients, pilocarpine 0.125% was positive in 80% of the tests. Eight patients who failed to show supersensitivity with Mecholyl were tested with pilocarpine and five of the eight were shown to be supersensitive. We concluded that pilocarpine, in this concentration is not only an adequate substitute for Mecholyl 2.5%, but is a more sensitive testing substance in unilateral cases, simply because it has a slightly stronger miotic action.

Adie Syndrome↗