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Biomedical subjects

P Brannan

Publications and source records attributed to P Brannan.

7 recordsLinked to original sources

Selecting and educating perioperative nurses for an ambulatory surgery setting.

A decision was made that review of technical skills for the perioperative and postanesthesia nurses hired from within the hospital was not necessary because they all had experience in their specialty areas. Those hired from other areas of the hospital will spend one month with a preceptor in the postanesthesia care area, one month in our short stay unit with a preceptor, and one month either in class or OR observation. All will have formal classes on anesthesia, fluid and electrolytes, and the philosophy of ambulatory surgery. These employees were released from their previous positions three months before the projected opening date of the new unit to allow them to learn the new skills. The patient care manager assigned responsibilities to the perioperative nurses hired from the main OR. They were asked to research needed equipment and supplies for various procedures in the different specialty areas. The patient care manager felt this would help them make a smooth transition to the new unit by making them feel like members of the team. My original hypothesis that perioperative nurses will not only rise to the occasion, but will far exceed our expectations will be tested when we move to the new ambulatory surgery unit. Although our opening date has been delayed, I am confident that our forethought and preparation will result in a smooth transition and an efficient staff.

Humans

Ion transport changes during calcitonin-induced intestinal secretion in man.

Previous studies have shown that synthetic salmon calcitonin (SCT) infused intravenously causes secretion of water and electrolytes in the jejunum of normal human subjects. The present experiments were carried out to learn more about the nature of this intestinal secretory process. During SCT- or synthetic human calcitonin (HCT)-induced intestinal secretion, the following observations were made: (1) There was no change in potential difference; (2) Cl was secreted against an electrochemical gradient; (3) unidirectional Na flux out of the lumen was decreased while the opposite flux was normal; (4) luminal pCO2 fell; (5) addition of glucose to the jejunal contents stimulated Na abdsorption, and this in turn counteracted the secretory effect of calcitonin. These findings suggest that calcitonin induces active Cl secretion and inhibits active Na absorption, and that HCO3 absorption is reduced by virtue of OH secretion; furthermore, jejunal glucose absorption and glucose-stimulated Na absorption are intact during calcitonin-induced secretion. Intravenous infusion of HCT caused intestinal secretion only when blood levels were much higher than occur physiologically; therefore, calcitonin is probably not a mediator of spontaneous variations of intestinal transport in normal people. However, because calcitonin induces secretion in the ileum as well as in the jejunum, hypercalcitonemia (within the range commonly found in patients with medullary carcinoma of the thyroid) could be a cause of severe secretory diarrhea.

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