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P Brettes

Publications and source records attributed to P Brettes.

8 recordsLinked to original sources

[The oral glucose tolerance test during normal pregnancy (author's transl)].

Physiological changes in carbohydrate tolerance were studied between the beginning and end of pregnancy. Amongst 145 oral glucose tolerance tests performed between the 9th and 40th weeks, results indicated that carbohydrate tolerance evolved throughout pregnancy. The first 24 weeks were characterised by a change in the shape of the glucose tolerance curve, in the form of horizontalisation of the terminal part, but with no increase in early blood glucose figures. It was only after the 24th week that mean blood glucose levels were seen to be increased. The interpretation of glucose tolerance tests during pregnancy should take these physiological changes into account. Critical values, above which diabetes must be suspected, are different at the beginning and end of pregnancy. The critical point would appear to be around the 24th week.

Adult

[Comparative study of oral and intravenous glucose tolerance test during pregnancy (author's transl)].

The glucose tolerance has been studied in 140 non diabetic pregnant women by successively oral and intravenous glucose tolerance test, as described respectively by O'Sullivan and Conard. The results of both tests are grossly similiar, and are affected on the same way by the evolution of the pregnancy. The intravenous glucose tolerance test is the easiest and the most reproducible; however some extra diabetic factors can interfere and mainly this test is not sensitive enough to discriminate between the pathologic and borderline situations. For all these reasons the intravenous glucose tolerance test can be used as a screening test for diabetes mellitus during pregnancy. The oral glucose tolerance test is necessary only when the K value is abnormal or subnormal.

Administration, Oral