[Teratogenic effect of dexamethasone phosphate directly injected into the amniotic fluid].
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Biomedical subjects
Publications and source records attributed to P Buck.
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It has been shown by comparative study of prepubertal ovaries both in the normal and ectopic positions that there is obvious follicular development which is quantitatively greater in ectopic ovaries. If the follicles reach the stage of cavitation they generally progress towards atresia. In any case it is possible however for follicular rupture to occur in the true sense with the onset of luteinisation. A perfectly developed corpus luteum has been observed in the ovary of a newborn infant.
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An eight week old baby who presented with a cholestatic jaundice had a bile plug in the ampulla of Vater. The plug was removal via a transduodenal approach. The bile plug syndrome is a rare cause of extrahepatic biliary cholestasis and is different from the inspissated bile syndrome in which the involvement is predominantly hepatocellular.
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Haemorragic cystitis is a well known complication of cyclophosphamide therapy. In the reported case, a 7 years old boy treated for lymphosarcoma, as an excretory urogram demonstrated important focal irregularity of the bladder wall. Cystoscopy revealed areas of important bullous oedema with generalized hyperemia. A biopsy disclosed normal urothelium raised by oedematous and congestive chorion and excluded a malignant tumor. Various kinds of endoscopic and surgical procedures are reported to control persisting hematuria after withdrawal of the cyclophosphamide treatment.
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