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Biomedical subjects

P Busoni

Publications and source records attributed to P Busoni.

At least 19 recordsLinked to original sources

[Trans-sacral extradural anesthesia in pediatrics].

Between 1988 and 1991 1,714 extradural anaesthesias by the transsacral or lumbosacral route have been performed. The anesthetic has always been mepivacaine 1%. Puncture between sacral vertebrae was practiced in 1,308 cases and by the lumbosacral approach in 406. Anaesthesia was for urogenital surgery in the majority of cases but also for orthopedic, abdominal and thoracic surgery. There have been 12 failures (0.7%) and a total of failures and complications was registered numbering 42 or 2.47%. No serious complication occurred.

Anesthesia, Caudal

The lumbosacral epidural block: a modified Taylor approach for abdominal urologic surgery in children.

We describe the lumbosacral epidural approach in 97 children undergoing abdominal urologic surgical procedures. Due to the rudimentary spinous process of the first sacral vertebra and the less prominent sacral angle, an appropriate upward inclination of the Tuohy needle in the midline is always possible in infants and small children. A catheter was easily inserted in every case and the technique was shown to be useful and safe for providing adequate intraoperative and postoperative pain control.

Adolescent

[Acute pulmonary edema in a 2-year-old child during peridural anesthesia].

A case of post obstructive pulmonary oedema in a two year old asthmatic child under epidural anaesthesia is described in this case report. The possible causes and mechanisms of this complication and its management are discussed. This discussion underlines that a minor degree of upper airway obstruction might have been capable of producing pulmonary oedema because of the altered lung function in this child.

Acute Disease

Effects of surgery and general or epidural anesthesia on plasma levels of cortisol, growth hormone and prolactin in infants under one year of age.

Twenty infants under one yr of age undergoing minor surgery were divided in two groups according to the type of anesthesia (epidural, Group 1, n = 10; general, Group 2, n = 10) which was randomly performed. Blood samples for cortisol (F), growth hormone (GH), and prolactin (PRL) determination were taken from each infant in baseline conditions, before surgery, and at the end of surgery. Mean plasma F levels in infants of group 2 rose significantly (p less than 0.01) before surgery to attend a maximum at the end of surgery (p less than 0.005). In infants of Group 1 a significant increase was also observed before surgery (p less than 0.05) but at the end of surgery mean plasma cortisol returned to levels comparable to baseline. Mean GH plasma levels were not significantly affected by both types of anesthesia, however an increase (not statistically significant) was observed at the end of surgery in both groups. Mean plasma PRL levels showed a significant increase before surgery (p less than 0.05 and p less than 0.01 in group 1 and 2, respectively) and a further increase at the end of surgery in both groups of infants (p less than 0.005). These results suggest that in infants under one yr of age both types of anesthetic procedures preceding surgery have no significant effect on plasma GH, but produce a significant increase of cortisol and prolactin mean plasma levels. The cortisol response to surgery and general or epidural anesthesia was similar to that reported in adults and prepubertal boys.(ABSTRACT TRUNCATED AT 250 WORDS)

Anesthesia, Epidural

The effect of general and regional anesthesia on oxygen-dependent microbicidal mechanisms of polymorphonuclear leukocytes in children.

The microbicidal activity of polymorphonuclear leukocytes (PMNL) was investigated in two groups of children undergoing hernia repair surgery. Group 1, after short general halothane anesthesia, received caudal analgesia, whereas group 2 received halothane anesthesia alone. Both groups showed a decrease in singlet oxygen production as demonstrated using chemiluminescence method. However, 24 hours after the end of surgery singlet oxygen production was fully recovered in the caudal analgesia group (group 1), whereas in the general anesthesia group (group 2), production was still significantly (P less than 0.01) depressed. It is concluded that halothane may be associated with PMNL impairment, perhaps in a time-dependent manner.

Adolescent