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Biomedical subjects

P C Ahn

Publications and source records attributed to P C Ahn.

4 recordsLinked to original sources

Electrocardiographic abnormalities in obese rats fed a commercially available liquid protein diet.

Male, obese and non-obese Osborne-Mendel rats were fed a commercially available liquid protein (LP) diet of poor nutritional quality in an amount proportional to that consumed by humans on this diet. Rats fed LP plus vitamins and minerals or a vitamin and mineral mixture only served as control groups. Electrocardiograms (ECG) were recorded weekly until the animals lost 45-50% of their original body weight. ECG's were normal in all groups at the start of the experiment. All rats consuming the LP diet only had arrhythmias. Intractable arrhythmias in the human have been of ventricular origin; in rats in this study various atrial disorders of an inconsistent nature were observed. Serum calcium was low in rats fed the LP diet, but normal in magnesium and potassium concentrations. Calcium, magnesium and potassium were in normal concentrations in cardiac and skeletal muscle, and in bone. Zinc and copper concentrations were low in hearts of rats fed the LP diet. The suggested role of calcium, magnesium and potassium in producing cardiac arrhythmias when subjects consume the liquid protein diet studied here as the sole source of calories is questioned.

Animals↗

Total fat and fatty acid composition of commercially available chocolate candies.

Forty different brands of chocolate candies were purchased in a supermarket. The wrappers were removed and coded, and the candy was re-wrapped in aluminum foil until analyzed. More than 60 percent of the samples had a polyunsaturated/saturated (P/S) ratio of less than 0.10. Although the candies examined had a higher carbohydrate than fat content, fat frequently contributed more calories in the candies containing more than 25 percent fat (15 of the 40 brands studied).

Cacao↗

Effect of dietary restrictions and source of rats on growth rate and efficiency of conversion of food into muscles, bones and organs.

Differences in weight of the body, six different skeletal muscles, epididymal fat pads, three different bones, spleen, heart, kidneys, testes and liver were observed in 21-day-old male Sprague-Dawley rats from two different suppliers. All rats were pair-fed a 10% casein diet ad libitum, 10%, 20%, 30% restricted for 4 or 8 weeks. Original body and tissue weight differences between the two strains of rats were maintained in all diets during the 4 and 8 week feeding periods. Trends in body and tissue weight changes due to dietary restriction were similar in both strains of rats. Diet restrictions for 4 or 8 weeks caused similar patterns of weight decrease in most tissues. Feed efficiency ratio (FER) was reduced significantly at the 20% and 30% restriction for 4 weeks only in the lighter strain of rats. FER was higher in the heavier strain than in the lighter strain of rats at all levels of diet restriction. Food conversion efficiency with reduced food intake was constant or decreased depending on the skeletal muscle studied; decreased significantly for epididymal fat pad, bone weight (one strain only), kidneys and liver (one strain only) with the 30% reduced diet for 4 weeks; and increased for bone length and testes weight. Therefore, significant deviations from ad libitum controls were found only at 30% diet restriction, and the wide differences in body and tissue weight of two strains of Sprague-Dawley rats did not affect the interpretation of results when fed the same restricted diets.

Adipose Tissue↗