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Biomedical subjects

P C Bonanno

Publications and source records attributed to P C Bonanno.

6 recordsLinked to original sources
PubMed1994

Safe dosages of lidocaine for facial analgesia.

A prospective study of serum lidocaine levels in cosmetic facial surgery patients was undertaken. The findings challenge the currently accepted minimal lethal dose (MLD) for lidocaine. Complete simultaneous facial analgesia (CSFA) was accomplished in an average of 15 minutes and the recommended dosage of lidocaine was exceeded by a mean of 52.8%. This study establishes a possible basis for redefining the maximum safe dosage for lidocaine in human subjects.

Anesthesia, Local↗
PubMed1992

Frey's syndrome: a preventable phenomenon.

Gustatory sweating, or Frey's syndrome, is a fairly common sequela of partial or radical parotidectomy, submaxillary gland surgery, or radical neck dissection. It is caused by an anastomotic communication with facial sweat glands by parasympathetic secretomotor nerve fibers intended for the excised parotid gland; treatments, whether surgical or topical, generally have been less than satisfactory. We present the first documented prophylactic approach to Frey's syndrome that is performed during and as part of parotidectomy. The surgery involves use of the superficial aponeurotic system (SMAS) as an interposing flap to interrupt the anastomotic nerve communication with the sweat glands. The SMAS is derived from the fascia in the periauricular cheek and neck area that is continuous with the platysma muscle. In a prospective study in 55 patients undergoing elective parotidectomy, the SMAS flap was elevated during the beginning of the operative procedure once it had been determined that fashioning of the flap would in no way compromise tumor excision. In all cases, at follow-up, there has been no clinical evidence of development of Frey's syndrome. We have shown that the development of the SMAS flap in parotid gland resections is an effective new approach both as a preventative measure against Frey's syndrome and as an aesthetic improvement over the usual defect typical of parotidectomies.

Humans↗