A patient with palpitations and bilateral pulmonary infiltrates.
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Female↗
Biomedical subjects
P C Fiehler
Publications and source records attributed to P C Fiehler.
Chronic necrotizing pulmonary aspergillosis treated by endobronchial amphotericin B.
Chronic necrotizing pulmonary aspergillosis is an indolent, locally invasive form of Aspergillus infection. Treatment options are limited and controversial. Resection is often curative if the patient has sufficient ventilatory reserve. Even though intravenous amphotericin B is effective in a few patients, toxicity limits its use. Aerosolized amphotericin B has proven ineffective. Anecdotal reports of intracavitary and endobronchial antifungal therapy show limited success. Our patient had unresectable chronic necrotizing pulmonary aspergillosis treated successfully with intracavitary instillation of amphotericin B, delivered via the flexible fiberoptic bronchoscope.
Amphotericin B↗
Occult pneumococcal bacteremia and empyema without preceding pulmonary parenchymal involvement.
We have presented a case of pneumococcal empyema without evidence of pulmonary parenchymal infection. We postulate that the pleural space was hematogenously seeded from an unexplained pneumococcemia. This manifestation of pneumococcal infection is unusual, particularly since the patient was receiving adequate antibiotic therapy before the radiologic or clinical appearance of the empyema. This emphasizes the need for diagnostic thoracentesis when the clinical situation changes, even after appropriate antimicrobial therapy is begun.
Ampicillin↗
Prolonged computer use and deep venous thrombosis.
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Computer Systems↗